Spindle cell neoplasm of skin: diagnostic dilemma.

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dc.contributor.authorJain, Manjulaen_US
dc.contributor.authorSingh, Sarikaen_US
dc.contributor.authorAgarwal, Kiranen_US
dc.date.accessioned2007-10-01en_US
dc.date.accessioned2009-05-29T11:17:15Z
dc.date.available2007-10-01en_US
dc.date.available2009-05-29T11:17:15Z
dc.date.issued2007-10-01en_US
dc.description.abstractPoorly differentiated, spindle cell malignancies, on sun damaged skin frequently pose a diagnostic challenge for pathologists. The vast majority of these neoplasms ultimately are diagnosed as either atypical fibroxanthoma (AFX), spindle cell melanoma (SCM), and very rarely as spindle cell squamous cell carcinoma (SCSCC), leiomyosarcoma or angiosarcoma. Light microscopic clues may suggest one of these neoplasms, but subtle and overlapping characteristics often render precise diagnosis impossible based on morphological features alone. Immunohistochemistry therefore is necessary to firmly and accurately diagnose the majority of spindle cell malignancies on sun damaged skin. Aim of this case report is to highlight the practical approach to such diagnostic dilemmas.en_US
dc.description.affiliationDepartment of Pathology, Lady Hardinge Medical College & Associated Hospitals, New Delhi.en_US
dc.identifier.citationJain M, Singh S, Agarwal K. Spindle cell neoplasm of skin: diagnostic dilemma. Indian Journal of Pathology & Microbiology. 2007 Oct; 50(4): 814-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/73349
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAged, 80 and overen_US
dc.subject.meshCarcinoma, Squamous Cell --pathologyen_US
dc.subject.meshDiagnosis, Differentialen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunohistochemistryen_US
dc.subject.meshKeratins --analysisen_US
dc.subject.meshMelanoma --pathologyen_US
dc.subject.meshS100 Proteins --analysisen_US
dc.subject.meshSarcoma --chemistryen_US
dc.subject.meshSkin Neoplasms --chemistryen_US
dc.subject.meshVimentin --analysisen_US
dc.subject.meshXanthomatosis --pathologyen_US
dc.titleSpindle cell neoplasm of skin: diagnostic dilemma.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
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