Dust-mites: effect on lipid peroxidation.

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dc.contributor.authorAtambay, Metinen_US
dc.contributor.authorKarabulut, Aysun Bayen_US
dc.contributor.authorAycan, Ozlem Makbuleen_US
dc.contributor.authorKilic, Eseren_US
dc.contributor.authorYazar, Suleymanen_US
dc.contributor.authorSaraymen, Recepen_US
dc.contributor.authorKaraman, Ulkuen_US
dc.contributor.authorDaldal, Nilgunen_US
dc.date.accessioned2006-03-08en_US
dc.date.accessioned2009-06-03T05:27:47Z
dc.date.available2006-03-08en_US
dc.date.available2009-06-03T05:27:47Z
dc.date.issued2006-03-08en_US
dc.description.abstractBACKGROUND: Dust-mites are present in our homes, feed on dead exfoliated skin and other organic material. It is also known that oxidative stress may lead to cellular damage that can be confirmed by markers of cellular disruption. Oxidative stress in various infective processes has been documented. We investigated whether house dust-mites cause oxidative stress in patients. METHODS: Products of lipid peroxidation in erythrocytes and lymphocytes were assessed by measuring malondialdehyde concentration. RESULTS: Our results showed that patients who had a positive skin test for dust-mite antigens and had dust-mites present in their houses (dust-mite positive) had increased erythrocyte malondialdehyde levels (62.39 [18.56] nmol/g-Hb) compared with those who were skin test positive, dust-mite negative (45.45 [10.82]) or skin test negative, dust-mite negative (42.20 [5.68]). They also had significantly higher levels of lymphocyte malondialdehyde (4.22 [0.55] nmol/g-protein) compared with those who were skin test positive, dust-mite negative (3.46 [0.29]) or skin test negative, dust-mite negative (1.25 [0.31]; p <0.05). However, there was no statistically significant difference between the malondialdehyde levels of dust-mite negative/skin test positive and dust-mite negative/skin test negative patients. CONCLUSION: Increased malondialdehyde activity in lymphocytes and erythrocytes in the dust-mite positive/skin test positive group shows the presence of the oxidative stress in patients with dust-mite infestation.en_US
dc.description.affiliationDepartment of Parasitology, Inonu University, Medical Faculty, Malatya, Turkey.en_US
dc.identifier.citationAtambay M, Karabulut AB, Aycan OM, Kilic E, Yazar S, Saraymen R, Karaman U, Daldal N. Dust-mites: effect on lipid peroxidation. National Medical Journal of India. 2006 Mar-Apr; 19(2): 75-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/118384
dc.language.isoengen_US
dc.source.urihttps://www.nmji.inen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAllergens --adverse effectsen_US
dc.subject.meshAntigensen_US
dc.subject.meshAsthma --blooden_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshChilden_US
dc.subject.meshDust --analysisen_US
dc.subject.meshErythrocytes --immunologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLipid Peroxidation --immunologyen_US
dc.subject.meshLymphocytes --immunologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMalondialdehyde --agonistsen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshOxidative Stress --immunologyen_US
dc.subject.meshPyroglyphidae --pathogenicityen_US
dc.subject.meshRhinitis --blooden_US
dc.subject.meshRisk Assessmenten_US
dc.subject.meshSkin Testsen_US
dc.titleDust-mites: effect on lipid peroxidation.en_US
dc.typeJournal Articleen_US
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