Gestational trophoblastic disease in 2005.

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dc.contributor.authorTherasakvichya, Suwaniten_US
dc.date.accessioned2009-05-27T18:23:53Z
dc.date.available2009-05-27T18:23:53Z
dc.date.issued2005-10-28en_US
dc.descriptionChotmaihet Thangphaet. 22 references.en_US
dc.description.abstractGestational trophoblastic diseases are still problematic in our practice. Event the incidence is in generally decreasing. And the development of Medicine in this decade can elucidate some parts of pathophysiology at cellular and molecular levels. However, malignant changes still can not be prevented. Approximately 20% of patients will develop malignant sequelae requiring administration of chemotherapy after evacuation of hydatidiform moles. Most patients with postmolar gestational trophoblastic disease will have non-metastatic molar proliferation or invasive moles, but gestational choriocarcinomas and metastatic disease can develop in this setting. Gestational choriocarcinoma occurs approximately 50% after term pregnancies, 25% after molar pregnancies, and the remainder after other gestational events. Although much rarer than hydatidiform moles or gestational choriocarcinomas, placental site trophoblastic tumors can develop after any type of pregnancy. For optimal management, practicing obstetrician-gynecologists should be able to diagnose and manage primary molar pregnancies, diagnose and stage malignant gestational trophoblastic neoplasia, and assess risk in women with malignant gestational trophoblastic neoplasia. This chapter views some points which may be useful for evidence-based practice in modern Medicine.en_US
dc.description.affiliationGynecologic Oncology Division, Department of Obstetrics & Gynecology, Faculty of Medicine, Siriraj Hospital, Mahidol University.en_US
dc.identifier.citationTherasakvichya S. Gestational trophoblastic disease in 2005. Journal of the Medical Association of Thailand. 2005 Oct; 88 Suppl 2(): S119-23en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/39064
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshFemaleen_US
dc.subject.meshGestational Trophoblastic Neoplasms --epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshNeoplasm Metastasisen_US
dc.subject.meshNeoplasm Stagingen_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy Complications, Neoplastic --epidemiologyen_US
dc.titleGestational trophoblastic disease in 2005.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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