Detection of autoantibodies against 3,5,3'-triiodothyronine in a hyperthyroid patient (a case report).

Simple item page
dc.contributor.authorJoseph, L Jen_US
dc.contributor.authorDesai, K Ben_US
dc.contributor.authorMehta, M Nen_US
dc.date.accessioned1991-01-01en_US
dc.date.accessioned2009-06-02T13:01:32Z
dc.date.available1991-01-01en_US
dc.date.available2009-06-02T13:01:32Z
dc.date.issued1991-01-01en_US
dc.description.abstractA 35-year-old female patient was evaluated for thyroid function and was found to be hyperthyroid clinically and by laboratory tests. During the course of treatment with neomercazole, she developed a bizarre picture with consistently low T3 levels irrespective of her clinical thyroid status and other laboratory tests like serum T4 and TSH levels. The serum of the patient when analysed for the presence of autoantibodies was positive for those against T3. The presence of T3 autoantibodies was confirmed by other laboratory techniques like assessment of blank values in radioimmunoassay, binding of T3-125I to isolated gamma globulin and starch gel electrophoresis. Autoantibodies were found to be present only against T3 and not against. T4 The affinity constant of T3 antibodies was 4 x 10(9) lit. mol-1 as determined by Scatchard plot analysis while total binding capacity was 23 x 10(-11) mol/L.en_US
dc.description.affiliationDepartment of Paediatrics, Sion Hospital, Sion, Bombay, Maharashtra.en_US
dc.identifier.citationJoseph LJ, Desai KB, Mehta MN. Detection of autoantibodies against 3,5,3'-triiodothyronine in a hyperthyroid patient (a case report). Journal of Postgraduate Medicine. 1991 Jan; 37(1): 44-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/117310
dc.language.isoengen_US
dc.source.urihttps://www.jpgmonline.comen_US
dc.subject.meshAdulten_US
dc.subject.meshAutoantibodies --analysisen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshHyperthyroidism --immunologyen_US
dc.subject.meshThyroxine --immunologyen_US
dc.subject.meshTriiodothyronine --immunologyen_US
dc.titleDetection of autoantibodies against 3,5,3'-triiodothyronine in a hyperthyroid patient (a case report).en_US
dc.typeCase Reportsen_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Journal of Postgraduate Medicine