Immunofluorescence profile of discoid lupus erythematosus.

Simple item page
dc.contributor.authorBharti, Shreekant
dc.contributor.authorDogra, Sunil
dc.contributor.authorSaikia, Biman
dc.contributor.authorWalker, Ranjana Minz
dc.contributor.authorChhabra, Seema
dc.contributor.authorSaikia, Uma Nahar
dc.date.accessioned2016-01-15T11:29:21Z
dc.date.available2016-01-15T11:29:21Z
dc.date.issued2015-10
dc.description.abstractThe direct immunofluorescence (DIF) of skin in conjunction with histopathology gives the best diagnostic yield. It is invaluable in confirming the diagnosis of small vessel vasculitides and bullous lesions of the skin and can be used as an additional tool to pinpoint the diagnosis of systemic and localized autoimmune diseases involving the skin. This study was undertaken to analyze the strength of DIF vis‑à‑vis histopathology in the diagnosis of discoid lupus erythematosus (DLE) and at the same time to elaborate the specific immunofluorescence findings in the lesions of DLE. The clinical profile and cutaneous lesions of 75 patients with DLE are described. DIF was positive in 68% and histopathology in 60% of cases. The most common immunoreactant was IgG at the dermoepidermal junction, followed by IgM and IgA. A conclusive diagnosis of DLE could be achieved satisfactorily in 64 cases (85%) by a combination of the two techniques.en_US
dc.identifier.citationBharti Shreekant, Dogra Sunil, Saikia Biman, Walker Ranjana Minz, Chhabra Seema, Saikia Uma Nahar. Immunofluorescence profile of discoid lupus erythematosus. Indian Journal of Pathology & Microbiology. 2015 Oct-Dec 58(4): 479-482.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/170503
dc.language.isoenen_US
dc.source.urihttps://www.ijpmonline.org/article.asp?issn=0377-4929;year=2015;volume=58;issue=4;spage=479;epage=482;aulast=Bhartien_US
dc.subjectDirect immunofluorescenceen_US
dc.subjectdiscoid lupus erythematosusen_US
dc.subjectskinen_US
dc.titleImmunofluorescence profile of discoid lupus erythematosus.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijpm2015v58n4p479.pdf
Size:
1.32 MB
Format:
Adobe Portable Document Format
Description:
Brief Communication
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Indian Journal of Pathology & Microbiology