Pituitary adenomas: immunohistochemical: study of 90 cases.

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dc.contributor.authorKasantikul, Ven_US
dc.contributor.authorShuangshoti, Sen_US
dc.date.accessioned2009-05-27T20:19:19Z
dc.date.available2009-05-27T20:19:19Z
dc.date.issued1990-09-01en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractPituitary tumors from 90 patients were investigated using immunohistochemical study and the results were correlated with clinical records. There were 32 benign prolactinomas and two malignant counterparts, 13 growth hormone positive tumors. 10 corticotropic adenomas, and 10 gonadotropic tumors. Four tumors showed positivity for both prolactin and growth hormone, one prolactin and gonadotropin. An example of mixed, luteinizing hormone, prolactin and growth hormone was observed. Additionally, there was an adenoma composed of two compartments secreting prolactin and growth hormone. One patient had a recurrent gonadotropin adenoma after surgical removal of the original prolactinoma. Fifteen tumors were negative for all hormones and most were nonfunctioning clinically. The clinicopathologic correlations were found to be good for prolactinoma, growth hormone positive tumors and for tumors producing both prolactin and growth hormones causing a combined feature of hyperprolactinemia and acromegaly.en_US
dc.description.affiliationDepartment of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.en_US
dc.identifier.citationKasantikul V, Shuangshoti S. Pituitary adenomas: immunohistochemical: study of 90 cases. Journal of the Medical Association of Thailand. 1990 Sep; 73(9): 514-21en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/42782
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdenoma --chemistryen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunohistochemistryen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPituitary Hormones --analysisen_US
dc.subject.meshPituitary Neoplasms --chemistryen_US
dc.titlePituitary adenomas: immunohistochemical: study of 90 cases.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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