Vitamin C status in cancer patients and healthy subjects from the local population of Pokhara.

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dc.contributor.authorAdhikari, Den_US
dc.contributor.authorBaxi, Jen_US
dc.contributor.authorNagamma, Ten_US
dc.contributor.authorAzhari, Sen_US
dc.contributor.authorSingh, P Pen_US
dc.date.accessioned2009-05-28T04:13:43Z
dc.date.available2009-05-28T04:13:43Z
dc.date.issued2006-07-08en_US
dc.descriptionKathmandu University Medical Journal.en_US
dc.description.abstractOBJECTIVES: To assess vitamin C status by determining plasma ascorbic acid level in 55 cancer patients and 55 matched normal subjects serving as control. METHODS: The proven cancer patients were selected from those attending Manipal Teaching Hospital, Pokhara. Matched controls were from the staff of Manipal Teaching Hospital or attendants of the patients. Plasma ascorbic acid was determined by the method of Natelson. Unpaired student 't' test was used for the statistical evaluation. Statistical analysis was done by SPSS version 9 software. RESULTS: The mean level of vitamin C in normal subjects and patients was 1.03+/-0.26 mg/dl and 0.90+/-0.30 mg/dl respectively. None of the subjects in either group had deficient status (<0.2 mg/dl). Although its status was normal in both the groups but patients had lower level than normal subjects. Smokers and alcohol consumers had significantly lower level than non-smoker and non-alcoholics. CONCLUSION: In the local population, vitamin C deficiency is not an etiologic factor in malignancy. Smoking and alcohol adversely affects the status of this vitamin.en_US
dc.description.affiliationDepartment of Biochemistry, Manipal College of Medical Sciences, Deep Heights, Pokhara, Nepal. deepakadhikari@rediffmail.comen_US
dc.identifier.citationAdhikari D, Baxi J, Nagamma T, Azhari S, Singh PP. Vitamin C status in cancer patients and healthy subjects from the local population of Pokhara. Kathmandu University Medical Journal. 2006 Jul-Sep; 4(3): 302-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/46630
dc.language.isoengen_US
dc.source.urihttps://www.kumj.com.npen_US
dc.source.urihttps://kumj.com.np/ftp/issue/15/302-306.pdfen_US
dc.subject.meshAge Distributionen_US
dc.subject.meshAgeden_US
dc.subject.meshAlcohol Drinking --adverse effectsen_US
dc.subject.meshAntioxidants --metabolismen_US
dc.subject.meshAscorbic Acid --blooden_US
dc.subject.meshAscorbic Acid Deficiency --blooden_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHospitals, Teachingen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeoplasms --epidemiologyen_US
dc.subject.meshNepal --epidemiologyen_US
dc.subject.meshNutrition Assessmenten_US
dc.subject.meshNutrition Policyen_US
dc.subject.meshNutritional Requirementsen_US
dc.subject.meshNutritional Statusen_US
dc.subject.meshPopulation Surveillanceen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSex Distributionen_US
dc.subject.meshSmoking --adverse effectsen_US
dc.subject.meshSocioeconomic Factorsen_US
dc.titleVitamin C status in cancer patients and healthy subjects from the local population of Pokhara.en_US
dc.typeJournal Articleen_US
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