Inferior vena cava thrombosis in a case of amoebic liver abscess: Is hypercomplementemia responsible for this rare entity.
Date
2014-04
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Abstract
Among the liver abscesses, thrombosis of the inferior vena cava (IVC) has been
reported mainly in amoebic liver abscess (ALA) caused by Entamoeba histolytica
(E.H). It is an unusual complication especially in paediatric age group. Association
of hypercomplementemia and IVC thrombosis has not been discussed previously.
Published data suggest that E.H can activate the complement system and can
cause hypercomplementemia. A very few studies suggest that complement
activation and hypercomplementemia are associated with thrombus formation.
We describe a paediatric case of ALA complicated by IVC thrombosis extending
to the right atrium and discuss the possible role of hypercomplementemia in
causation of IVC thrombosis in cases of ALA.
Description
Keywords
Amoebic liver abscess, complement proteins 3 and 4, inferior vena cava thrombosis
Citation
Chandelia Sudha, Jain Sarika, Yadav Dinesh Kumar, Dubey Nand Kishore. Inferior vena cava thrombosis in a case of amoebic liver abscess: Is hypercomplementemia responsible for this rare entity. Indian Journal of Pathology & Microbiology. 2014 Apr-Jun 57 (2): 329-331.