Impact of initial topical medical therapy on short‑term quality of life in newly diagnosed patients with primary glaucoma.

dc.contributor.authorArora, Vishal
dc.contributor.authorBali, Shveta Jindal
dc.contributor.authorGupta, Sanjeev Kumar
dc.contributor.authorVashisht, Praveen
dc.contributor.authorAgarwal, Tushar
dc.contributor.authorSreenivas, Vishnubhatla
dc.contributor.authorDada, Tanuj
dc.date.accessioned2016-01-13T05:51:59Z
dc.date.available2016-01-13T05:51:59Z
dc.date.issued2015-06
dc.description.abstractPurpose: To evaluate the impact of initial topical medical therapy on newly diagnosed glaucoma patients using the Indian Vision Function Questionnaire (IND-VFQ33). Patients and Methods: The IND-VFQ33 was used to evaluate the quality of life (QoL) in 62 newly diagnosed patients with moderate to severe primary glaucoma and 60 healthy controls. IND-VFQ33 is a 33 item QoL assessment tool with three domains: General functioning, psychosocial impact and visual symptoms. The glaucoma patients were started on medical therapy and the QoL assessment was repeated after 3 months. Results: Glaucoma patients (mean age: 55.6 ± 9.6 years, range 40–77 years) and controls (mean age: 54.9 ± 6.7 years, 42–73 years) were matched with respect to age (P = 0.72), gender (P = 0.91) and literacy (P = 0.18). Glaucoma patients had significantly worse QoL as compared to controls at baseline across all the three domains (P < 0.001). 3 months after initiation of treatment, the overall QoL life significantly worsened from baseline with a decrease in general functioning (P < 0.001) and psychosocial impact (P = 0.041). Visual acuity in better eye significantly co-related to poor QoL at baseline (P < 0.001) and at 3 months (P = 0.04). In addition, the use of >2 topical medications significantly co-related to poor QoL at 3 months (P = 0.01). Conclusions: Evaluation using the IND-VFQ33 revealed that newly diagnosed glaucoma patients have a significant worsening of QoL after initiation of topical ocular hypotensive therapy. This should be an important consideration when educating patients about the disease and its therapy.en_US
dc.identifier.citationArora Vishal, Bali Shveta Jindal, Gupta Sanjeev Kumar, Vashisht Praveen, Agarwal Tushar, Sreenivas Vishnubhatla, Dada Tanuj. Impact of initial topical medical therapy on short‑term quality of life in newly diagnosed patients with primary glaucoma. Indian Journal of Ophthalmology. 2015 June; 63(6): 511-515.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/170388
dc.language.isoenen_US
dc.source.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550984/en_US
dc.subjectIndian Vision Function Questionnaireen_US
dc.subjectprimary glaucomaen_US
dc.subjectquality of lifeen_US
dc.titleImpact of initial topical medical therapy on short‑term quality of life in newly diagnosed patients with primary glaucoma.en_US
dc.typeArticleen_US
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