An echo-cardiographic (M-mode & 2D) analysis of thalassaemia major.
dc.contributor.author | Senior, R | en_US |
dc.contributor.author | Batabyal, S K | en_US |
dc.contributor.author | Dutta, R N | en_US |
dc.contributor.author | Guha, S | en_US |
dc.contributor.author | Dutta, S | en_US |
dc.contributor.author | Bhattacharji, T D | en_US |
dc.contributor.author | Kundu, S C | en_US |
dc.contributor.author | Maity, A K | en_US |
dc.contributor.author | Kar, C C | en_US |
dc.date.accessioned | 1990-01-01 | en_US |
dc.date.accessioned | 2009-05-27T04:22:26Z | |
dc.date.available | 1990-01-01 | en_US |
dc.date.available | 2009-05-27T04:22:26Z | |
dc.date.issued | 1990-01-01 | en_US |
dc.description.abstract | 25 cases of thalassaemia major were studied by 2D and M-mode echocardiography. A significantly increased (p less than 0.001) mean value (100.8 +/- 27.37 msec, range 80 to 140 msec) of A2-E (early relaxation period) interval on M-mode was observed in thalassemia in comparison to mean level (82.6 +/- 5.7, range 60 to 100 msec) of control population. No significant differences were noted in FS % (fractional shortening) and EF% (ejection fraction) when compared to corresponding normal values respectively. Mean serum iron concentration (142.2 +/- 29.1 micrograms/dl, range 102 to 192 micrograms/dl) was significantly higher in thalassaemia as compared to normal population (mean 106.3 +/- 11.4 micrograms/dl, range 75 to 120 micrograms/dl). There was also a direct correlation between serum iron concentration and A2-E interval. 11 patients (44%) showed abnormal A2-E interval but only 3 patients (12%) showed abnormal percentage of FS and EF. It is therefore concluded that A2-E interval will help to detect early left ventricular dysfunction much before overt and irreversible heart failure becomes manifest and which will also help to optimise transfusion and chelation therapy. | en_US |
dc.description.affiliation | Dept. of Biochemistry, Singh Hospital, Calcutta. | en_US |
dc.identifier.citation | Senior R, Batabyal SK, Dutta RN, Guha S, Dutta S, Bhattacharji TD, Kundu SC, Maity AK, Kar CC. An echo-cardiographic (M-mode & 2D) analysis of thalassaemia major. Indian Heart Journal. 1990 Jan-Feb; 42(1): 73-6 | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/4273 | |
dc.language.iso | eng | en_US |
dc.source.uri | https://indianheartjournal.com | en_US |
dc.subject.mesh | Adolescent | en_US |
dc.subject.mesh | Child | en_US |
dc.subject.mesh | Echocardiography | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Hemoglobins --analysis | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Thalassemia --physiopathology | en_US |
dc.title | An echo-cardiographic (M-mode & 2D) analysis of thalassaemia major. | en_US |
dc.type | Journal Article | en_US |
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