An echo-cardiographic (M-mode & 2D) analysis of thalassaemia major.

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dc.contributor.authorSenior, Ren_US
dc.contributor.authorBatabyal, S Ken_US
dc.contributor.authorDutta, R Nen_US
dc.contributor.authorGuha, Sen_US
dc.contributor.authorDutta, Sen_US
dc.contributor.authorBhattacharji, T Den_US
dc.contributor.authorKundu, S Cen_US
dc.contributor.authorMaity, A Ken_US
dc.contributor.authorKar, C Cen_US
dc.date.accessioned1990-01-01en_US
dc.date.accessioned2009-05-27T04:22:26Z
dc.date.available1990-01-01en_US
dc.date.available2009-05-27T04:22:26Z
dc.date.issued1990-01-01en_US
dc.description.abstract25 cases of thalassaemia major were studied by 2D and M-mode echocardiography. A significantly increased (p less than 0.001) mean value (100.8 +/- 27.37 msec, range 80 to 140 msec) of A2-E (early relaxation period) interval on M-mode was observed in thalassemia in comparison to mean level (82.6 +/- 5.7, range 60 to 100 msec) of control population. No significant differences were noted in FS % (fractional shortening) and EF% (ejection fraction) when compared to corresponding normal values respectively. Mean serum iron concentration (142.2 +/- 29.1 micrograms/dl, range 102 to 192 micrograms/dl) was significantly higher in thalassaemia as compared to normal population (mean 106.3 +/- 11.4 micrograms/dl, range 75 to 120 micrograms/dl). There was also a direct correlation between serum iron concentration and A2-E interval. 11 patients (44%) showed abnormal A2-E interval but only 3 patients (12%) showed abnormal percentage of FS and EF. It is therefore concluded that A2-E interval will help to detect early left ventricular dysfunction much before overt and irreversible heart failure becomes manifest and which will also help to optimise transfusion and chelation therapy.en_US
dc.description.affiliationDept. of Biochemistry, Singh Hospital, Calcutta.en_US
dc.identifier.citationSenior R, Batabyal SK, Dutta RN, Guha S, Dutta S, Bhattacharji TD, Kundu SC, Maity AK, Kar CC. An echo-cardiographic (M-mode & 2D) analysis of thalassaemia major. Indian Heart Journal. 1990 Jan-Feb; 42(1): 73-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/4273
dc.language.isoengen_US
dc.source.urihttps://indianheartjournal.comen_US
dc.subject.meshAdolescenten_US
dc.subject.meshChilden_US
dc.subject.meshEchocardiographyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHemoglobins --analysisen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshThalassemia --physiopathologyen_US
dc.titleAn echo-cardiographic (M-mode & 2D) analysis of thalassaemia major.en_US
dc.typeJournal Articleen_US
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