Psychological problems and quality of life in children with thalassemia.

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dc.contributor.authorShaligram, Den_US
dc.contributor.authorGirimaji, S Cen_US
dc.contributor.authorChaturvedi, S Ken_US
dc.date.accessioned2007-08-06en_US
dc.date.accessioned2009-05-30T15:41:32Z
dc.date.available2007-08-06en_US
dc.date.available2009-05-30T15:41:32Z
dc.date.issued2007-08-06en_US
dc.description.abstractOBJECTIVE: The study is aimed to assess psychological problems and quality of life (QOL) in children with thalassemia. METHODS: Thirty-nine children (8-16 yr) with transfusion dependent thalassemia attending day care services for blood transfusion were assessed for psychological problems using the Childhood Psychopathology Measurement Schedule and QOL was assessed using the EQ-5D. RESULTS: Forty-four percent of the children had psychological problems and 74% had a poor QOL. Anxiety-related symptoms (67%), emotional problems, particularly depression (62%) and conduct problems (49%) were the main findings. The children were most likely to report impaired QOL due to severe difficulties in pain/discomfort (64%) dimension, followed by depression and mobility problems of equal severity (33%). The side effects of chelation were an independent predictor of psychological problems and impaired QOL. Also psychological problems were a significant predictor of impaired QOL. CONCLUSION: The recognition and management of the psychological problems that accompany chronic physical illnesses including thalassemia would optimize treatment outcomes and QOL.en_US
dc.description.affiliationDepartment of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India. dpka.sha@gmail.comen_US
dc.identifier.citationShaligram D, Girimaji SC, Chaturvedi SK. Psychological problems and quality of life in children with thalassemia. Indian Journal of Pediatrics. 2007 Aug; 74(8): 727-30en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/83860
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/icb/icbai.shtmlen_US
dc.subject.meshAdolescenten_US
dc.subject.meshChi-Square Distributionen_US
dc.subject.meshChilden_US
dc.subject.meshChronic Diseaseen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLinear Modelsen_US
dc.subject.meshMaleen_US
dc.subject.meshPsychiatric Status Rating Scalesen_US
dc.subject.meshQuality of Lifeen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshThalassemia --psychologyen_US
dc.titlePsychological problems and quality of life in children with thalassemia.en_US
dc.typeJournal Articleen_US
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