Retrospective analysis of colistin-resistant bacteria in a tertiary care centre in India

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dc.contributor.authorSinha, Sen_US
dc.contributor.authorSahu, Sen_US
dc.contributor.authorPati, Jen_US
dc.contributor.authorRay, Ben_US
dc.contributor.authorPattnaik, SKen_US
dc.date.accessioned2020-04-10T01:42:04Z
dc.date.available2020-04-10T01:42:04Z
dc.date.issued2019-03
dc.description.abstractThe incidence of carbapenem-resistant Enterobacteriaceae has been steadily rising. The morbidity, mortality and financial implications of such patients are significant. We did a retrospective analysis of the case records of 11 patients who had culture report positive for pan drug-resistant (PDR) organisms. There were total 15 isolates of PDR organisms in 11 patients. These were associated with catheter-associated urinary tract infections (7), tracheitis (4), bacteraemia (2), meningitis (1) and soft-tissue infection (1). Average APACHE II score was 23.72 (range 7-36) indicating patients with multiple co-morbidities and organ dysfunction. The average length of hospital stay was 60.72 (25-123) days. The overall mortality rate was 81.81 per cent, while PDR infection-related mortality was 18.18 per cent. Strict implementation of antibiotic stewardship programme is essential to limit use and prevent abuse of colistin.en_US
dc.identifier.affiliationsDepartment of Critical Care Medicine, Apollo Hospitals, Bhubaneswar, Indiaen_US
dc.identifier.affiliationsDepartment of Microbiology, Apollo Hospitals, Bhubaneswar, Indiaen_US
dc.identifier.citationSinha S, Sahu S, Pati J, Ray B, Pattnaik SK. Retrospective analysis of colistin-resistant bacteria in a tertiary care centre in India. Indian Journal of Medical Research. 2019 Mar; 149(3): 418-422en_US
dc.identifier.issn0971-5916
dc.identifier.issn0975-9174
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/195829
dc.languageenen_US
dc.publisherIndian Council of Medical Researchen_US
dc.relation.issuenumber3en_US
dc.relation.volume149en_US
dc.source.urihttps://dx.doi.org/10.4103/ijmr.IJMR_1388_17en_US
dc.subjectAntibiotic abuseen_US
dc.subjectcarbapenem resistanceen_US
dc.subjectcolistinen_US
dc.subjectmortalityen_US
dc.subjectpan drug-resistanceen_US
dc.titleRetrospective analysis of colistin-resistant bacteria in a tertiary care centre in Indiaen_US
dc.typeJournal Articleen_US
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