Role of serum phosphate level in cardiovascular events in non-CKD patients

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dc.contributor.authorKumar, Arvinden_US
dc.contributor.authorSingh, Premen_US
dc.contributor.authorKhan, Mohd. Imranen_US
dc.contributor.authorAlam, Mehtaben_US
dc.date.accessioned2020-04-09T07:42:27Z
dc.date.available2020-04-09T07:42:27Z
dc.date.issued2019-07
dc.description.abstractBackground: Serum phosphate level correlate with atherosclerosis in both animal models and humans with advanced chronic kidney disease and coronary calcification is a known impact of higher serum phosphate, but whether this relationship exists among individuals with Non-CKD is unknown. we conducted this study to observe role of higher serum phosphate level in cardiovascular comorbidities like MI and CHF in Non-CKD patients.Methods: In this observational study, 300 patients were enrolled, half of the patients having Clinical features or positive biochemical markers (Troponin-I for MI and serum BNP for CHF) suggestive of myocardial infarction and heart failure were taken as case group and half of the subjects were taken as control group with similar baseline characteristics. All participants in this study were consenting and more than 18 years of age.Results: The mean value of serum phosphate level in case group was 4.41±1.40 while in control group was 3.19±1.07 showing statistically significant difference (p-value <0.001). In case group 65% patients were having MI with higher serum phosphate level (4.22±1.40).Conclusion: Higher serum phosphate level is related to increased cardiovascular morbidities even in non-CKD patients.en_US
dc.identifier.affiliationsDepartment of Medicine, Ganesh Shankar Vidyarthi Memorial Medical College, Kanpur, Uttar Pradesh, Indiaen_US
dc.identifier.citationKumar Arvind, Singh Prem, Khan Mohd. Imran, Alam Mehtab. Role of serum phosphate level in cardiovascular events in non-CKD patients. International Journal of Advances in Medicine. 2019 Jul; 6(4): 1182-1187en_US
dc.identifier.issn2349-3925
dc.identifier.issn2349-3933
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/194371
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber4en_US
dc.relation.volume6en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3933.ijam20193266en_US
dc.subjectCardiovascular morbiditiesen_US
dc.subjectCongestive heart failureen_US
dc.subjectMyocardial infractionen_US
dc.subjectSerum phosphate levelen_US
dc.titleRole of serum phosphate level in cardiovascular events in non-CKD patientsen_US
dc.typeJournal Articleen_US
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