Alterations in duodenal disaccharidases in chronic smokers.

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dc.contributor.authorKaura, Den_US
dc.contributor.authorBhasin, D Ken_US
dc.contributor.authorRana, S Ven_US
dc.contributor.authorKatyal, Ren_US
dc.contributor.authorVaiphei, Ken_US
dc.contributor.authorSingh, Ken_US
dc.date.accessioned2001-03-18en_US
dc.date.accessioned2009-05-29T02:41:39Z
dc.date.available2001-03-18en_US
dc.date.available2009-05-29T02:41:39Z
dc.date.issued2001-03-18en_US
dc.description.abstractOBJECTIVE: To assess the effect of smoking on activity of intestinal disaccharidases. METHODS: The study was conducted on patients with non-ulcer dyspepsia who were smokers (n=20) or non-smokers (n=20). Smokers were classified according to smoking index into mild, moderate and heavy smokers. Biopsy specimens were taken from the second part of the duodenum at endoscopy and examined histologically, and for disaccharidase (lactase, sucrase, maltase and trehalase) activities. RESULTS: Mean duration of symptoms was more in smokers than in non-smokers. None of the smokers had endoscopic evidence of duodenal inflammation. Lactase and trehalase levels were significantly decreased in smokers. There was no difference in enzyme levels between mild smokers and non-smokers. Decreased lactase, maltase and trehalase activities were observed in moderate smokers compared to mild smokers. Duration of symptoms had no relation to enzyme activities. CONCLUSIONS: Intestinal disaccharidase levels are diminished by smoking.en_US
dc.description.affiliationDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh.en_US
dc.identifier.citationKaura D, Bhasin DK, Rana SV, Katyal R, Vaiphei K, Singh K. Alterations in duodenal disaccharidases in chronic smokers. Indian Journal of Gastroenterology. 2001 Mar-Apr; 20(2): 62-3en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/64449
dc.language.isoengen_US
dc.source.urihttps://www.indianjgastro.comen_US
dc.subject.meshAdulten_US
dc.subject.meshBiopsyen_US
dc.subject.meshChi-Square Distributionen_US
dc.subject.meshDisaccharidases --metabolismen_US
dc.subject.meshDuodenum --enzymologyen_US
dc.subject.meshDyspepsia --etiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshSmoking --adverse effectsen_US
dc.titleAlterations in duodenal disaccharidases in chronic smokers.en_US
dc.typeJournal Articleen_US
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