Serum protein polymorphisms and malaria in Madya Pradesh, India.

dc.contributor.authorThakur, Aen_US
dc.contributor.authorVerma, I Cen_US
dc.date.accessioned2009-05-27T14:36:44Z
dc.date.available2009-05-27T14:36:44Z
dc.date.issued1993-06-01en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractThe relationship of serum protein polymorphisms to the presence of malaria antibodies was studied in 473 muria gond tribal subjects from Bastar district, Central India, an area endemic for both P. falciparum and P. vivax infection. A control group of 100 subjects in Delhi, which has a low prevalence of malaria, was also studied. Serum proteins (transferrin, haptoglobin and albumin) were analyzed for polymorphic variants by starch gel electrophoresis. Malarial antibodies were assayed by enzyme linked immunosorbent assay (ELISA), while thin blood films were screened for the presence of malaria parasites. Among serum proteins transferrin CD variant showed significant correlation with malarial infection. There were no significant differences observed between Hp1 and Hp2 variants of haptoglobin in relation to presence of malarial antibodies. Statistical analysis for albumin variants was not attempted because the number of individuals showing abnormal bands was small.en_US
dc.description.affiliationDepartment of Pediatrics, All India Institute of Medical Sciences, New Delhi.en_US
dc.identifier.citationThakur A, Verma IC. Serum protein polymorphisms and malaria in Madya Pradesh, India. The Southeast Asian Journal of Tropical Medicine and Public Health. 1993 Jun; 24(2): 235-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/30600
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/publication.htmen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAntibodies, Protozoan --geneticsen_US
dc.subject.meshBlood Proteins --geneticsen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshGene Frequencyen_US
dc.subject.meshHaptoglobins --geneticsen_US
dc.subject.meshHumansen_US
dc.subject.meshMalaria, Falciparum --blooden_US
dc.subject.meshMalaria, Vivax --blooden_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPolymorphism, Geneticen_US
dc.subject.meshSerum Albumin --geneticsen_US
dc.subject.meshTransferrin --geneticsen_US
dc.titleSerum protein polymorphisms and malaria in Madya Pradesh, India.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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