Efficacy of single-dose mebendazole, polymorphic forms A and C, in the treatment of hookworm and Trichuris infections.

Simple item page
dc.contributor.authorCharoenlarp, Pen_US
dc.contributor.authorWaikagul, Jen_US
dc.contributor.authorMuennoo, Cen_US
dc.contributor.authorSrinophakun, Sen_US
dc.contributor.authorKitayaporn, Den_US
dc.date.accessioned2009-05-27T15:40:24Z
dc.date.available2009-05-27T15:40:24Z
dc.date.issued1993-12-01en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractA therapeutic trial of single mebendazole, 300 mg polymorph A, 300 mg polymorph C and 500 mg polymorph C, in the treatment of hookworm and Trichuris infections was carried out at primary schools in Southern Thailand. The total of 958 children were randomly allocated in seven treatment groups including the placebo control and the standard dose control (100 mg polymorph C bid for 3 days). The egg reduction rates and the cure rates of 300 mg and 500 mg polymorph C were similar, but inferior to those of the standard dose in both hookworm and Trichuris infections. The efficacy of single dose 300 mg polymorph A was not different from that of the placebo control (alpha = 0.05) in both infections.en_US
dc.description.affiliationDepartent of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.en_US
dc.identifier.citationCharoenlarp P, Waikagul J, Muennoo C, Srinophakun S, Kitayaporn D. Efficacy of single-dose mebendazole, polymorphic forms A and C, in the treatment of hookworm and Trichuris infections. The Southeast Asian Journal of Tropical Medicine and Public Health. 1993 Dec; 24(4): 712-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/33373
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/publication.htmen_US
dc.subject.meshChilden_US
dc.subject.meshDose-Response Relationship, Drugen_US
dc.subject.meshFeces --parasitologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHookworm Infections --drug therapyen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMebendazole --administration & dosageen_US
dc.subject.meshParasite Egg Counten_US
dc.subject.meshTrichuriasis --drug therapyen_US
dc.titleEfficacy of single-dose mebendazole, polymorphic forms A and C, in the treatment of hookworm and Trichuris infections.en_US
dc.typeClinical Trialen_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Southeast Asian Journal of Tropical Medicine and Public Health