Does radiofrequency ablation increase creatine kinase and troponin-T?

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dc.contributor.authorGupta, Aen_US
dc.contributor.authorHalankar, Sen_US
dc.contributor.authorVora, A Men_US
dc.contributor.authorLokhandwala, Y Yen_US
dc.date.accessioned1999-07-05en_US
dc.date.accessioned2009-05-27T04:26:51Z
dc.date.available1999-07-05en_US
dc.date.available2009-05-27T04:26:51Z
dc.date.issued1999-07-05en_US
dc.description.abstractRadiofrequency ablation produces a focal area of myocardial necrosis. Creatine kinase (total & MB fraction) and troponin-T were analysed in 54 patients who underwent electrophysiological study and radiofrequency ablation for atrioventricular nodal reentrant tachycardia, atrioventricular reentrant tachycardia and idiopathic ventricular tachycardia. The age of the patients was 36 +/- 12 years; 17 patients underwent slow pathway modification for atrioventricular nodal reentrant tachycardia, 26 patients underwent accessory pathway ablation and 11 patients underwent ablation for idiopathic ventricular tachycardia. There was no significant rise in creatine kinase, creatine kinase total & MB fraction and troponin-T in the patients who underwent slow pathway ablation for atrioventricular nodal reentrant tachycardia. In patients with atrioventricular reentrant tachycardia, there was no significant rise in creatine kinase and creatine kinase total & MB fraction levels, while troponin-T levels rose from 0.13 +/- 0.06 to 0.29 +/- 0.16 eta g/ml (p < 0.05). There was an increase in creatine kinase, creatine kinase total & MB fraction and troponin-T levels after idiopathic ventricular tachycardia ablation from 68.4 +/- 44.9 to 138.0 +/- 81.7 IU (p < 0.05), 2.77 +/- 3.34 to 25.2 +/- 19.8 IU (p < 0.05) and 0.09 +/- 0.04 to 0.34 +/- 0.08 eta g/ml (p < 0.001) respectively. Radiofrequency ablation of atrioventricular nodal reentrant tachycardia does not cause any significant myocardial damage to raise any cardiac enzymes. Ablation of atrioventricular reentrant tachycardia results in only minor injury causing rise in only troponin-T levels. However, ventricular tachycardia ablation results in significant myocardial injury raising all the cardiac enzymes.en_US
dc.description.affiliationDepartment of Cardiology, KEM Hospital, Mumbai.en_US
dc.identifier.citationGupta A, Halankar S, Vora AM, Lokhandwala YY. Does radiofrequency ablation increase creatine kinase and troponin-T? Indian Heart Journal. 1999 Jul-Aug; 51(4): 418-21en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/5314
dc.language.isoengen_US
dc.source.urihttps://indianheartjournal.comen_US
dc.subject.meshAdulten_US
dc.subject.meshArrhythmias, Cardiac --blooden_US
dc.subject.meshCatheter Ablationen_US
dc.subject.meshCreatine Kinase --blooden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshTachycardia, Atrioventricular Nodal Reentry --blooden_US
dc.subject.meshTroponin T --blooden_US
dc.titleDoes radiofrequency ablation increase creatine kinase and troponin-T?en_US
dc.typeJournal Articleen_US
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