Cutaneous manifestations in patients with chronic renal failure on hemodialysis.

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dc.contributor.authorUdayakumar, Pen_US
dc.contributor.authorBalasubramanian, Sen_US
dc.contributor.authorRamalingam, K Sen_US
dc.contributor.authorLakshmi, Chembollien_US
dc.contributor.authorSrinivas, C Ren_US
dc.contributor.authorMathew, Anil Cen_US
dc.date.accessioned2009-05-28T08:29:28Z
dc.date.available2009-05-28T08:29:28Z
dc.date.issued2006-03-19en_US
dc.description.abstractBACKGROUND: Chronic renal failure (CRF) presents with an array of cutaneous manifestations. Newer changes are being described since the advent of hemodialysis, which prolongs the life expectancy, giving time for these changes to manifest. AIM: The aim of this study was to evaluate the prevalence of dermatologic problems among patients with chronic renal failure (CRF) undergoing hemodialysis. METHODS: One hundred patients with CRF on hemodialysis were examined for cutaneous changes. RESULTS: Eighty-two per cent patients complained of some skin problem. However, on examination, all patients had at least one skin lesion attributable to CRF. The most prevalent finding was xerosis (79%), followed by pallor (60%), pruritus (53%) and cutaneous pigmentation (43%). Other cutaneous manifestations included Kyrle's disease (21%); fungal (30%), bacterial (13%) and viral (12%) infections; uremic frost (3%); purpura (9%); gynecomastia (1%); and dermatitis (2%). The nail changes included half and half nail (21%), koilonychia (18%), onychomycosis (19%), subungual hyperkeratosis (12%), onycholysis (10%), splinter hemorrhages (5%), Mees' lines (7%), Muehrcke's lines (5%) and Beau's lines (2%). Hair changes included sparse body hair (30%), sparse scalp hair (11%) and brittle and lusterless hair (16%). Oral changes included macroglossia with teeth markings (35%), xerostomia (31%), ulcerative stomatitis (29%), angular cheilitis (12%) and uremic breath (8%). Some rare manifestations of CRF like uremic frost, gynecomastia and pseudo-Kaposi's sarcoma were also observed. CONCLUSIONS: CRF is associated with a complex array of cutaneous manifestations caused either by the disease or by treatment. The commonest are xerosis and pruritus and the early recognition of cutaneous signs can relieve suffering and decrease morbidity.en_US
dc.description.affiliationDepartment of Dermatology, PSG Hospitals, Peelamedu, Coimbatore, India.en_US
dc.identifier.citationUdayakumar P, Balasubramanian S, Ramalingam KS, Lakshmi C, Srinivas CR, Mathew AC. Cutaneous manifestations in patients with chronic renal failure on hemodialysis. Indian Journal of Dermatology, Venereology and Leprology. 2006 Mar-Apr; 72(2): 119-25en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/52686
dc.language.isoengen_US
dc.source.urihttps://www.ijdvl.comen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshChilden_US
dc.subject.meshFemaleen_US
dc.subject.meshHair Diseases --etiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshKidney Failure, Chronic --complicationsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMouth Mucosa --pathologyen_US
dc.subject.meshNail Diseases --etiologyen_US
dc.subject.meshPigmentation Disorders --etiologyen_US
dc.subject.meshPruritus --etiologyen_US
dc.subject.meshRenal Dialysisen_US
dc.subject.meshSkin Diseases --etiologyen_US
dc.subject.meshSkin Diseases, Infectious --etiologyen_US
dc.titleCutaneous manifestations in patients with chronic renal failure on hemodialysis.en_US
dc.typeJournal Articleen_US
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