Impact of Intra-Operative Fluid Therapy on Short Term Outcomes in Patients Undergoing Advanced Laparoscopic Colorectal Operations Performed for Colorectal Cancer.

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dc.contributor.authorAvula, Jyothien_US
dc.contributor.authorVarghese, Gigien_US
dc.contributor.authorYadav, Bijeshen_US
dc.contributor.authorChandy, Tony Thomsonen_US
dc.date.accessioned2020-11-18T10:18:46Z
dc.date.available2020-11-18T10:18:46Z
dc.date.issued2020-01
dc.description.abstractBACKGROUND There has been a recent shift in the operative approach in advanced colorectal operations where in laparoscopy is being used as the preferred modality of intra-abdominal access. Literature is not clear and there is no consensus with regards to the optimal intraoperative fluid requirements in these operations. Hence, we did a retrospective study of intraoperative fluid requirements for all laparoscopic advanced colorectal resection operations and looked at its impact on short term postoperative recovery.METHODSThis is a retrospective analysis of all patients who have undergone advanced laparoscopic colorectal resections in colorectal surgical unit in a single tertiary care centre in south India from January 2014 to June 2017. Data was collected from prospectively maintained electronic inpatient and outpatient charts. The outcomes analysed were postoperative morbidity and length of postoperative hospital stay with respect to intra-operative rate of intravenous (IV) fluid administration.RESULTSThere was a total of 201 laparoscopic advanced colorectal resections performed from January 2014 to June 2017. The median IV fluid rate was 5.2 ml/Kg/hr (SD-1.97). Seventy nine of 201 patients were documented to have morbidity based on Clavien-Dindo classification. Patients who received intraoperative IV fluids </= 5 ml/Kg/hr were categorised into the restrictive fluid regimen group and patients who received > 5 ml/Kg/hr were categorised into the liberal fluid regimen group. Out of the 79 patients with post-operative morbidity, there was a statistically significant difference between the restrictive fluid group 32/79 (40.5%) and the liberal fluid group 47/79 (59.5%) with a p value of 0.03.CONCLUSIONSIntra-operative liberal fluid management seems to be associated with increased postoperative morbidity in laparoscopic advanced colorectal resections.en_US
dc.identifier.affiliationsDepartment of Anaesthesia, CMC, Vellore, Tamilnadu, India.en_US
dc.identifier.affiliationsDepartment of Colorectal Surgery, CMC, Vellore, Tamilnadu, India.en_US
dc.identifier.affiliationsDepartment of Biostatistics, CMC, Vellore, Tamilnadu, India.en_US
dc.identifier.affiliationsDepartment of Anaesthesia, CMC, Vellore, Tamilnadu, Indiaen_US
dc.identifier.citationAvula Jyothi, Varghese Gigi, Yadav Bijesh, Chandy Tony Thomson. Impact of Intra-Operative Fluid Therapy on Short Term Outcomes in Patients Undergoing Advanced Laparoscopic Colorectal Operations Performed for Colorectal Cancer.. Journal of Evolution of Medical and Dental Sciences. 2020 Jan; 9(1): 29-32en_US
dc.identifier.issn2278-4802
dc.identifier.issn2278-4748
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/215303
dc.languageenen_US
dc.publisherAkshantala Enterprises Private Limiteden_US
dc.relation.issuenumber1en_US
dc.relation.volume9en_US
dc.source.urihttps://dx.doi.org//10.14260/jemds/2020/7en_US
dc.subjectLaparoscopyen_US
dc.subjectColorectal Surgeryen_US
dc.subjectIntraoperative Fluidsen_US
dc.subjectPostoperative Morbidityen_US
dc.titleImpact of Intra-Operative Fluid Therapy on Short Term Outcomes in Patients Undergoing Advanced Laparoscopic Colorectal Operations Performed for Colorectal Cancer.en_US
dc.typeJournal Articleen_US
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