Oral cancer among patients under the age of 35 years.
dc.contributor.author | Iype, E M | en_US |
dc.contributor.author | Pandey, M | en_US |
dc.contributor.author | Mathew, A | en_US |
dc.contributor.author | Thomas, G | en_US |
dc.contributor.author | Sebastian, P | en_US |
dc.contributor.author | Nair, M K | en_US |
dc.date.accessioned | 2001-07-08 | en_US |
dc.date.accessioned | 2009-06-02T11:37:32Z | |
dc.date.available | 2001-07-08 | en_US |
dc.date.available | 2009-06-02T11:37:32Z | |
dc.date.issued | 2001-07-08 | en_US |
dc.description.abstract | BACKGROUND: Cancer of the oral cavity is one of the commonest cancers among males. AIMS: To assess the aetiological factors, patient characteristics, treatment and the outcome in young patients with oral cancer. SETTINGS AND DESIGN: A retrospective descriptive study of patients under the age of 35 years with cancer of the oral cavity treated between 1982-1996, with the last follow-up till 2001, using the tumour registry data of Regional Cancer Centre (RCC), Trivandrum, Kerala, India. SUBJECT AND METHOD: The detailed clinical, treatment and follow-up data were obtained from the computerised records of RCC and recorded on a preset proforma. This was analysed with emphasis on age, sex, risk factors, site, histology, clinical extent and treatment methods and survival in the study group. STATISTICAL ANALYSIS: The survival analysis was carried by Kaplan-Meier method and the difference in survival was analysed using log-rank test. RESULTS: Out of 264 patients analysed, tongue was the commonest site identified in 136 (52%) patients followed by buccal mucosa in 69 (26%) patients. A male female ratio of 2.3:1 was observed with a significantly higher male preponderance in buccal mucosa (4.3:1). Prior exposure to tobacco or alcohol was noted in 59.4% patients, with more habitués in buccal mucosa cancer. Histological confirmation was present only in 83.7% patients and among them most were squamous cell carcinoma (85.9%). Radiotherapy, surgery or combined modalities of treatment were employed for majority of patients. The 5-year survival was 57.3%. T stage of the tumour was found to be significant in predicting disease free survival (P=0.03). CONCLUSIONS: The importance of early detection for clinical down staging is stressed. There is a need to investigate the aetiology of intra oral cancers in younger patients since a significant proportion (almost 40%) of these patients do not have associated risk factors for cancer. | en_US |
dc.description.affiliation | Department of Surgical Oncology, Epidemiology and Clinical studies, Community Oncology and Radiation Oncology, Regional Cancer Centre, Medical College, Thiruvananthapuram - 695 011, India. emathewiype@yahoo.com | en_US |
dc.identifier.citation | Iype EM, Pandey M, Mathew A, Thomas G, Sebastian P, Nair MK. Oral cancer among patients under the age of 35 years. Journal of Postgraduate Medicine. 2001 Jul-Sep; 47(3): 171-6 | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/116345 | |
dc.language.iso | eng | en_US |
dc.source.uri | https://www.jpgmonline.com | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Carcinoma, Squamous Cell --epidemiology | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Follow-Up Studies | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | India --epidemiology | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Mouth Neoplasms --epidemiology | en_US |
dc.subject.mesh | Retrospective Studies | en_US |
dc.subject.mesh | Risk Factors | en_US |
dc.subject.mesh | Survival Analysis | en_US |
dc.subject.mesh | Time Factors | en_US |
dc.title | Oral cancer among patients under the age of 35 years. | en_US |
dc.type | Journal Article | en_US |
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