Oral cancer among patients under the age of 35 years.

Simple item page
dc.contributor.authorIype, E Men_US
dc.contributor.authorPandey, Men_US
dc.contributor.authorMathew, Aen_US
dc.contributor.authorThomas, Gen_US
dc.contributor.authorSebastian, Pen_US
dc.contributor.authorNair, M Ken_US
dc.date.accessioned2001-07-08en_US
dc.date.accessioned2009-06-02T11:37:32Z
dc.date.available2001-07-08en_US
dc.date.available2009-06-02T11:37:32Z
dc.date.issued2001-07-08en_US
dc.description.abstractBACKGROUND: Cancer of the oral cavity is one of the commonest cancers among males. AIMS: To assess the aetiological factors, patient characteristics, treatment and the outcome in young patients with oral cancer. SETTINGS AND DESIGN: A retrospective descriptive study of patients under the age of 35 years with cancer of the oral cavity treated between 1982-1996, with the last follow-up till 2001, using the tumour registry data of Regional Cancer Centre (RCC), Trivandrum, Kerala, India. SUBJECT AND METHOD: The detailed clinical, treatment and follow-up data were obtained from the computerised records of RCC and recorded on a preset proforma. This was analysed with emphasis on age, sex, risk factors, site, histology, clinical extent and treatment methods and survival in the study group. STATISTICAL ANALYSIS: The survival analysis was carried by Kaplan-Meier method and the difference in survival was analysed using log-rank test. RESULTS: Out of 264 patients analysed, tongue was the commonest site identified in 136 (52%) patients followed by buccal mucosa in 69 (26%) patients. A male female ratio of 2.3:1 was observed with a significantly higher male preponderance in buccal mucosa (4.3:1). Prior exposure to tobacco or alcohol was noted in 59.4% patients, with more habitués in buccal mucosa cancer. Histological confirmation was present only in 83.7% patients and among them most were squamous cell carcinoma (85.9%). Radiotherapy, surgery or combined modalities of treatment were employed for majority of patients. The 5-year survival was 57.3%. T stage of the tumour was found to be significant in predicting disease free survival (P=0.03). CONCLUSIONS: The importance of early detection for clinical down staging is stressed. There is a need to investigate the aetiology of intra oral cancers in younger patients since a significant proportion (almost 40%) of these patients do not have associated risk factors for cancer.en_US
dc.description.affiliationDepartment of Surgical Oncology, Epidemiology and Clinical studies, Community Oncology and Radiation Oncology, Regional Cancer Centre, Medical College, Thiruvananthapuram - 695 011, India. emathewiype@yahoo.comen_US
dc.identifier.citationIype EM, Pandey M, Mathew A, Thomas G, Sebastian P, Nair MK. Oral cancer among patients under the age of 35 years. Journal of Postgraduate Medicine. 2001 Jul-Sep; 47(3): 171-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/116345
dc.language.isoengen_US
dc.source.urihttps://www.jpgmonline.comen_US
dc.subject.meshAdulten_US
dc.subject.meshCarcinoma, Squamous Cell --epidemiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMouth Neoplasms --epidemiologyen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSurvival Analysisen_US
dc.subject.meshTime Factorsen_US
dc.titleOral cancer among patients under the age of 35 years.en_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Journal of Postgraduate Medicine