Nerve cell markers in ossifying fibromyxoid tumour of soft parts.

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dc.contributor.authorShet, Ten_US
dc.contributor.authorDesai, Sen_US
dc.contributor.authorKane, Sen_US
dc.contributor.authorVora, Ien_US
dc.date.accessioned2001-04-09en_US
dc.date.accessioned2009-05-29T12:08:04Z
dc.date.available2001-04-09en_US
dc.date.available2009-05-29T12:08:04Z
dc.date.issued2001-04-09en_US
dc.description.abstractReported herein are two benign ossifying fibromyxoid tumors (OFMTs) of the soft tissues in axilla and terminal phalanx respectively. Both cases on immunohistochemistry (IHC) showed reactivity for vimentin, S-100 protein and glial fibrillary acidic protein (GFAP) antibodies. In addition, a focal/diffuse strong positivity for neurofilament (NF) and neuron specific enolase (NSE) was observed. Electron microscopy in one instance revealed abundant intermediate filaments, primitive cell junctions and a focally present external lamina. In the light of nerve cell differentiation of these tumors and the similarity of IHC profile and EM features of OFMT to a poorly differentiated malignant peripheral nerve sheath tumor (MPNST); it is suggested that OFMT is a variably differentiated PNST rather than a simple Schwannian neoplasm as is believed.en_US
dc.description.affiliationDepartment of Pathology, BYL Nair Ch Hospital, Mumbai.en_US
dc.identifier.citationShet T, Desai S, Kane S, Vora I. Nerve cell markers in ossifying fibromyxoid tumour of soft parts. Indian Journal of Pathology & Microbiology. 2001 Apr; 44(2): 163-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/74265
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshGlial Fibrillary Acidic Protein --metabolismen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNerve Sheath Neoplasms --diagnosisen_US
dc.subject.meshOssification, Heterotopicen_US
dc.subject.meshPhosphopyruvate Hydratase --metabolismen_US
dc.subject.meshS100 Proteins --metabolismen_US
dc.subject.meshSoft Tissue Neoplasms --diagnosisen_US
dc.subject.meshTumor Markers, Biological --metabolismen_US
dc.subject.meshVimentin --metabolismen_US
dc.titleNerve cell markers in ossifying fibromyxoid tumour of soft parts.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
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