Cardiovascular abnormalities in severe scrub typhus

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dc.contributor.authorNadda, Nishanten_US
dc.contributor.authorMahajan, Sanjayen_US
dc.contributor.authorKaushik, Madanen_US
dc.contributor.authorMerwaha, Rajeeven_US
dc.date.accessioned2020-11-18T09:59:33Z
dc.date.available2020-11-18T09:59:33Z
dc.date.issued2019-09
dc.description.abstractBackground: Himachal Pradesh is an endemic area for scrub typhus. If not treated early, it can lead to life threatening complications, affecting various systems of the body. Hence, this study was done with an objective to study the cardiovascular abnormalities in patients of severe scrub typhus.Methods: Authors conducted a hospital-based study in Departments of Medicine and Cardiology, of a tertiary care hospital in Sub-himalayan region in patients of severe scrub typhus from June 2016 to May 2017.Results: Thirty-two (55%) patients were aged <60 years with female preponderance (72%).   Electrocardiographic changes included sinus tachycardia in 56 (97%), axis deviation in 5(9%), ST-T changes in 3(5%) and atrial fibrillation in 1(2%). Echocardiographic changes included tricuspid regurgitation in 14(24%), pericardial effusion in 4(7%), myocarditis in 1(2%) and Regional wall motion abnormality in 1(2%). Left ventricular ejection fraction >45% in 47 (81%) and <45% in 11(19%).  Fifty-one patients had hypotension at presentation and 49 (90%) of them improved. Interestingly, 10 of 11 patients with reduced EF (<45%) survived whereas 6 of total 7 patients, who died, had preserved EF (>45 %).Conclusions: Severe scrub typhus manifested with ST/T changes, myocarditis, pericardial effusion, arrhythmias, shock and patients with reduced EF on Echocardiography had better outcome.en_US
dc.identifier.affiliationsDepartment of Internal Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Cardiology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.citationNadda Nishant, Mahajan Sanjay, Kaushik Madan, Merwaha Rajeev. Cardiovascular abnormalities in severe scrub typhus. International Journal of Research in Medical Sciences. 2019 Sep; 7(9): 3385-3390en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/211705
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber9en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-6012.ijrms20193918en_US
dc.subjectEchocardiographic changesen_US
dc.subjectElectrocardiographic changesen_US
dc.subjectScrub typhus,en_US
dc.titleCardiovascular abnormalities in severe scrub typhusen_US
dc.typeJournal Articleen_US
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