Propofol for pediatric radiotherapy.

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dc.contributor.authorPunj, Jyotsnaen_US
dc.contributor.authorBhatnagar, Sushmaen_US
dc.contributor.authorSaxena, Abhaen_US
dc.contributor.authorMishra, Seemaen_US
dc.contributor.authorKannan, T Ren_US
dc.contributor.authorPanigrahi, Manasen_US
dc.contributor.authorPandey, Vipinen_US
dc.date.accessioned2002-06-26en_US
dc.date.accessioned2009-05-30T16:29:48Z
dc.date.available2002-06-26en_US
dc.date.available2009-05-30T16:29:48Z
dc.date.issued2002-06-26en_US
dc.description.abstractOBJECTIVE: Pediatric radiotherapy is a day care procedure. In children, anaesthesia is necessary to prevent movement during the therapy. Traditionally intramuscular ketamine is used for these procedure because of its inherent safety in a child who used to be left alone in the cobalt room. METHODS: This study was designed to explore the efficacy of propofol and ketamine in pediatric radiotherapy in nineteen children. The inclusion criteria was a child fasting for six hours with no fever or URTI in the past week. A child coming to the radiotherapy (RT) unit without an intravenous cannula was given intramuscular ketamine 10 mg/kg and taken for the procedure. Before the child recovered from anaesthesia an intravenous cannula, 20-22G, Vasofix was inserted for subsequent sittings of RT. The child coming with an intravenous cannula was given propofol 2.5 mg/kg with xylocaine (0.1 mg/kg) without adrenaline. The parameters recorded were pulse rate, oxygen saturation and respiratory rate-baseline to every 30 seconds till five minutes. Onset time, recovery time, oral feeding time and any untoward effects like nausea, vomiting, nystagmus were also noted. RESULT: The drug was graded on a scale of 0-10 according to parental acceptability where 0 is the worst and 10 is the best acceptability. The mean (+/-SD) of all the measured parameters were calculated and compared between the two groups. CONCLUSION: Propofol was associated with faster onset, better recovery, early oral feeding time, no nausea and vomiting and better parental acceptability. There was no hypotension, bradycardia and oxygen saturation at 60 seconds, which was between 94-95%, was easily treatable with supplementation of oxygen by face mask.en_US
dc.description.affiliationUnit of Anesthesiology, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, Ansari Nagar, New Delhi. jyotsna_punj@yahoo.comen_US
dc.identifier.citationPunj J, Bhatnagar S, Saxena A, Mishra S, Kannan TR, Panigrahi M, Pandey V. Propofol for pediatric radiotherapy. Indian Journal of Pediatrics. 2002 Jun; 69(6): 495-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/84622
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/icb/icbai.shtmlen_US
dc.subject.meshAnesthetics, Dissociative --administration & dosageen_US
dc.subject.meshAnesthetics, Intravenous --administration & dosageen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshKetamine --administration & dosageen_US
dc.subject.meshMaleen_US
dc.subject.meshNeoplasms --radiotherapyen_US
dc.subject.meshPropofol --administration & dosageen_US
dc.subject.meshStatistics, Nonparametricen_US
dc.titlePropofol for pediatric radiotherapy.en_US
dc.typeJournal Articleen_US
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