Management of pseudohypoparathyroidism in pregnancy: a rare entity

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Date
2019-09
Authors
Sinha, Mrinalini
Ara, Anjum
Chug, Indu C.
Hansadah, Saunri
Goyal, Avani
Journal Title
Journal ISSN
Volume Title
Publisher
Medip Academy
Abstract
Pseudohypoparathyroidism is a very rare genetic disorder and during pregnancy poses multiple challenges related to its monitoring and management. Authors present the case of a  30year old primigravida who was a diagnosed case of pseudohypoparathyroidism since 22 yrs of age, presented to our obs/gynae OPD at 5+5 wks of POG. She was managed by serial monitoring of serum calcium, phosphate and vitamin D throughout  pregnancy with careful dose modification of calcium from 1gm to 3.5gm daily and vitamin D from  0.5mcg  to 1.5mcg daily. During her course of pregnancy, she developed gestational hypothyroidism, gestational diabetes mellitus, intrahepatic cholestasis of pregnancy and gestational hypertension which were controlled and managed successfully. She had an elective caesarean section at 37+6 wks POG for transverse lie. Both maternal and perinatal outcome were good. Patient was discharged with advice to continue with her monitoring of serum calcium, phosphate, vitamin D along with supplementation of calcium and vitamin D life long.
Description
Keywords
Pseudohypoparathyroidism, Serum calcium, Vitamin D
Citation
Sinha Mrinalini, Ara Anjum, Chug Indu C., Hansadah Saunri, Goyal Avani. Management of pseudohypoparathyroidism in pregnancy: a rare entity. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2019 Sep; 8(9): 3798-3800