Clinico-Bacteriological Profile of Chronic Suppurative Otitis Media in a Teaching Hospital of Uttar Pradesh

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dc.contributor.authorRana, Amit Kumaren_US
dc.contributor.authorYadav, Akankshaen_US
dc.contributor.authorJuyal, Deepaken_US
dc.contributor.authorSinha, Anant Narayanen_US
dc.contributor.authorSayana, Ashutoshen_US
dc.contributor.authorPrasad, Surendraen_US
dc.date.accessioned2019-12-02T10:30:44Z
dc.date.available2019-12-02T10:30:44Z
dc.date.issued2018-01
dc.description.abstractBackground: Chronic suppurative otitis media (CSOM) is a commonly encountered infection of the middle ear. It cancause extra cranial and intracranial complications and involves considerable morbidity. Although it is a global disease, its incidence has remained relatively higher in resource-constrained countries. Due to its recurrent nature and the development of resistant pathogenic organisms, control of infection poses a greatest therapeutic challenge. Knowledge of the local microbial flora in CSOM is essential for initiating empirical therapy. The objective of our study was to examine the current bacteriological profile and antibiotic sensitivity pattern to locally available antibiotics in CSOM. Methods: A total of 157 patients clinically diagnosed of CSOM were enrolled in the study and the samples were obtained from each patient using sterile cotton swabs and were processed as per standard microbiological techniques. Antibiotic sensitivity to ten locally available antibiotics was analyzed. Antibiotic susceptibility testing for bacterial isolates was conducted using Kirby-Bauer disc diffusion method. Results: Out of total 157 swabs bacterial growth was seen in 144 (91.72%) with Pseudomonas aeruginosa (28.5%) and Staphylococcus aureus (22.9%) being the most common bacterial isolates. Among the antibiotics tested amikacin (88.3%), ciprofloxacin (78.9%) and cotrimoxazole (78.2%) were found to be most active against all the isolates, whereas maximum resistance was seen for ampicillin (45.8%). Poor hygiene 79 (50.3%) and pond/river bath 51 (32.5%) were the two most common predisposing factors associated with CSOM. Conclusion: In the era of continuously increasing drug resistance among bacteria, periodic monitoring of the bacterial isolates causing CSOM and their antibiogram with clinical correlation is very important. Local antimicrobial susceptibility data should be utilized for formulating antibiotic policy for every institution. Our results will surely help in the modification of hospital’s current antibiotic policy and also will optimize the therapy to patients.en_US
dc.identifier.affiliationsSenior Resident, Department of Otorhinolaryngology, Rohilkhand Medical College & Hospital, Bareilly, Uttar Pradesh – 243006en_US
dc.identifier.affiliationsPG 3rd Year, Department of Otorhinolaryngology, Rohilkhand Medical College & Hospital, Bareilly, Uttar Pradesh – 243006en_US
dc.identifier.affiliationsAssistant Professor, Department of Microbiology, Govt. Doon Medical College, Patelnagar, Dehradun, Uttarakhand – 248001en_US
dc.identifier.affiliationsAssociate Professor, Department of Physiology, Govt. Doon Medical College, Patelnagar, Dehradun, Uttarakhand – 248001en_US
dc.identifier.affiliationsDirector Medical Education, Uttarakhand and Professor & Head, Department of Surgery, Govt. Doon Medical College, Patelnagar, Dehradun, Uttarakhand – 248001en_US
dc.identifier.affiliationsProfessor, Department of Otorhinolaryngology, Rohilkhand Medical College & Hospital, Bareilly, Uttar Pradesh – 243006.en_US
dc.identifier.citationRana Amit Kumar, Yadav Akanksha, Juyal Deepak, Sinha Anant Narayan, Sayana Ashutosh, Prasad Surendra . Clinico-Bacteriological Profile of Chronic Suppurative Otitis Media in a Teaching Hospital of Uttar Pradesh. Annals of International medical and Dental Research. 2018 Jan; 4(1): 11-15en_US
dc.identifier.issn2395-2822
dc.identifier.issn2395-2814
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/187657
dc.languageenen_US
dc.publisherSociety for Health Care & Research Developmenten_US
dc.relation.issuenumber1en_US
dc.relation.volume4en_US
dc.source.urihttps://www.doi.org/10.21276/aimdr.2018.4.1.EN4en_US
dc.subjectAmikacinen_US
dc.subjectCSOMen_US
dc.subjectDrug resistanceen_US
dc.subjectOtorrheaen_US
dc.subjectPseudomonasen_US
dc.subjectStaphylococcusen_US
dc.titleClinico-Bacteriological Profile of Chronic Suppurative Otitis Media in a Teaching Hospital of Uttar Pradeshen_US
dc.typeJournal Articleen_US
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