Vancomycin intermediate and vancomycin resistant Staphylococcus aureus: an upcoming threat

Simple item page
dc.contributor.authorPatel, ASen_US
dc.contributor.authorBhabhor, UHen_US
dc.contributor.authorMullan, SA.en_US
dc.date.accessioned2025-08-13T11:44:22Z
dc.date.available2025-08-13T11:44:22Z
dc.date.issued2025-07
dc.description.abstractBackground: Either community or hospital settings, Staphylococcus aureus is a significant pathogen that causes mild localized infections of the skin to potentially fatal systemic infections. The increasing evidence of reduced vancomycin susceptibility (RVS) and vancomycin resistance in clinical MRSA isolates is troubling. There aren't many therapeutic options available for such isolates. We have identified the most current pattern of antimicrobial resistance and specifically evaluated Staphylococcus aureus's susceptibility profile to vancomycin. vancomycin-intermediate Staphylococcus aureus and isolates of Staphylococcus aureus that are resistant to vancomycin. Methods: Non-duplicate, consecutive isolates of S. aureus obtained from January 2021 to June 2022 were subject to antimicrobial susceptibility testing using standard disk diffusion tests or epsilometer tests according to the clinical laboratory standards institute 2021 requirements. Results: The total of 315 S. aureus were isolated during study period. Swab and pus sample shows highest isolation followed by other sample types. A total of 202 (64.1%) isolates were MRSA, while 111 (35.2%) were Inducible clindamycin positive ( ICR Positive). Antibiotic resistance observed is, penicillin (303/315, 96.1%), Ofloxacin (266/315, 84.4%), levofloxacin (255/315, 80.9%), Azithromycin (190/315, 60.3%) followed by other class of antibiotic groups. In our study Vancomycin , Linezolid and Teicoplanin are 100% sensitive. Vancomycin resistance is not noted in any isolates but we have 7 Vancomycin intermate isolates. Conclusions: Gate keeping in advent use of antibiotic is paramount importance to control the antibiotic resistance. As well as continuous laboratory monitoring of various antibiotic resistance pattern is needed.en_US
dc.identifier.affiliationsDepartment of Microbiology, Government Medical College, Surat, Gujarat, Indiaen_US
dc.identifier.affiliationsDepartment of Microbiology, Government Medical College, Bhavnagar, Gujarat, Indiaen_US
dc.identifier.affiliationsDepartment of Microbiology, Government Medical College, Surat, Gujarat, Indiaen_US
dc.identifier.citationPatel AS, Bhabhor UH, Mullan SA. . Vancomycin intermediate and vancomycin resistant Staphylococcus aureus: an upcoming threat . International Journal of Research in Medical Sciences. 2025 Jul; 13(7): 2884-2889en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/254208
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber7en_US
dc.relation.volume13en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-6012.ijrms20252022en_US
dc.subjectVancomycin-resistant Staphylococcus aureusen_US
dc.subjectVancomycin-intermediate Staphylococcus aureusen_US
dc.subjectMethicillin-resistant Staphylococcus aureusen_US
dc.subjectStaphylococcus aureusen_US
dc.subjectVancomycinen_US
dc.titleVancomycin intermediate and vancomycin resistant Staphylococcus aureus: an upcoming threaten_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
ijrms2025v13n7p2884.pdf
Size:
288.52 KB
Format:
Adobe Portable Document Format
Download
Collections
International Journal of Research in Medical Sciences