Acetylcholinesterase activities in cerebrospinal fluid of patients with Plasmodium falciparum cerebral malaria.

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Date
1985-09-01
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Abstract
Serum cholinesterase (CHE) and acetylcholinesterase (ACHE) in cerebrospinal fluid (CSF) were determined simultaneously in 30 patients with P. falciparum cerebral malaria. Nineteen patients (63%) had low serum CHE and mean value of this serum enzyme in 30 patients was significantly lower than that of non-infected group. CSF ACHE levels were found to be significantly lower than those of normal subjects reported earlier. Post-treatment in the hospital for one week, both serum CHE and CSF ACHE levels in 9 convalescent subjects increased significantly. These findings indicated that both serum CHE and CSF ACHE levels were depressed in patients with cerebral malaria and increased on recovery.
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The Southeast Asian Journal of Tropical Medicine and Public Health.
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Areekul S, Churdchu K, Yamarat P. Acetylcholinesterase activities in cerebrospinal fluid of patients with Plasmodium falciparum cerebral malaria. The Southeast Asian Journal of Tropical Medicine and Public Health. 1985 Sep; 16(3): 431-4