Effects of cessation of a policy of neonatal fluconazole prophylaxis on fungal resurgence.

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dc.contributor.authorDutta, Sourabhen_US
dc.contributor.authorMurki, Srinivasen_US
dc.contributor.authorVarma, Sanjeeven_US
dc.contributor.authorNarang, Anilen_US
dc.contributor.authorChakrabarti, Arunalokeen_US
dc.date.accessioned2005-12-21en_US
dc.date.accessioned2009-05-27T05:04:21Z
dc.date.available2005-12-21en_US
dc.date.available2009-05-27T05:04:21Z
dc.date.issued2005-12-21en_US
dc.description.abstractFluconazole has been used as prophylaxis against systemic fungal infections in preterm neonates. We conducted a study to determine whether cessation of a policy of prophylactic fluconazole results in a resurgence of fungal infections in a unit. Neonates born in the 3 epoches: A 36-month pre-Fluconazole prophylaxis epoch (Group 1), a 21-month Fluconazole prophylaxis epoch (Group 2) and a 39-month post Fluconazole prophylaxis epoch (Group 3) were compared for incidence and onset of fungal sepsis and resistance patterns. There was a decline in the incidence of fungal sepsis from Group 1 to Group 2, and it remained stable from Group 2 to Group 3. There was no significant difference in resistance to Fluconazole and to any of the azoles in Groups 1, 2 and 3 respectively.en_US
dc.description.affiliationDivision of Neonatology, Department of Pediatrics, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh 160 012, India. sourabhdutta@yahoo.co.inen_US
dc.identifier.citationDutta S, Murki S, Varma S, Narang A, Chakrabarti A. Effects of cessation of a policy of neonatal fluconazole prophylaxis on fungal resurgence. Indian Pediatrics. 2005 Dec; 42(12): 1226-30en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/7921
dc.language.isoengen_US
dc.source.urihttps://indianpediatrics.neten_US
dc.subject.meshAntifungal Agents --therapeutic useen_US
dc.subject.meshFemaleen_US
dc.subject.meshFluconazole --therapeutic useen_US
dc.subject.meshFungemia --epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshIntensive Care Units, Neonatal --organization & administrationen_US
dc.subject.meshMaleen_US
dc.subject.meshOrganizational Policyen_US
dc.subject.meshRetrospective Studiesen_US
dc.titleEffects of cessation of a policy of neonatal fluconazole prophylaxis on fungal resurgence.en_US
dc.typeJournal Articleen_US
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