Leukemia as a second malignancy.

Simple item page
dc.contributor.authorUppin, Megha Sen_US
dc.contributor.authorPaul, T Roshnien_US
dc.contributor.authorRajappa, Senthilen_US
dc.contributor.authorGayathri, Ken_US
dc.contributor.authorJacob, Rachelen_US
dc.contributor.authorUppin, Shantveer Gen_US
dc.date.accessioned2007-07-22en_US
dc.date.accessioned2009-05-29T10:45:13Z
dc.date.available2007-07-22en_US
dc.date.available2009-05-29T10:45:13Z
dc.date.issued2007-07-22en_US
dc.description.abstractTo study the occurrence of leukemia as a second malignancy following various primary solid and hematological malignancies. Total 11 cases of leukemia presenting as a second malignancy were studied over a period of 15 years from 1990 to 2005. The primary malignancies included carcinoma breast (4), multiple myeloma (3) and one each of Hodgkin's lymphoma, mediastinal germ cell tumor, papillary carcinoma thyroid and myxopapillary ependymoma. Ten patients had received chemotherapy with combination radiotherapy in six patients. The commonest type of leukemia was AML-M2. The cyogenetic test results were available in three cases. The secondary leukemia showed aggressive behaviour and all patients on follow-up died within a period of one month. The risk benefit ratio of chemotherapy and radiotherapy should be considered before starting the patients on treatment. A high degree of suspicion and follow up with hematological parameters is required for therapy related complications.en_US
dc.description.affiliationDepartment of Pathology, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad.en_US
dc.identifier.citationUppin MS, Paul TR, Rajappa S, Gayathri K, Jacob R, Uppin SG. Leukemia as a second malignancy. Indian Journal of Pathology & Microbiology. 2007 Jul; 50(3): 644-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/72775
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshAntineoplastic Agents --adverse effectsen_US
dc.subject.meshCombined Modality Therapyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLeukemia, Myeloid, Acute --epidemiologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeoplasms --therapyen_US
dc.subject.meshNeoplasms, Second Primary --epidemiologyen_US
dc.subject.meshRadiotherapy --adverse effectsen_US
dc.titleLeukemia as a second malignancy.en_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Pathology & Microbiology