Use of L-Arginine for Inhaled Nitric Oxide (iNO) Dependent Hepatopulmonary Syndrome (HPS) Post-Liver Transplant

Simple item page
dc.contributor.authorKataria, Mohnishen_US
dc.contributor.authorRastogi, Abhinaven_US
dc.contributor.authorManjoor, Sajaaden_US
dc.contributor.authorTanwar, Himanshuen_US
dc.contributor.authorPatibandla, Sivajien_US
dc.contributor.authorSingh, Vishal V.en_US
dc.date.accessioned2020-11-18T10:18:12Z
dc.date.available2020-11-18T10:18:12Z
dc.date.issued2020-03
dc.description.abstractHepatopulmonary syndrome (HPS) is one of the recognised complications of liver cirrhosis which warrants urgent liver transplantation. The symptoms usually improve post transplantation but might take 6-12 months to resolve completely. Severe hypoxemia post liver transplantation, especially when done for hepatopulmonary syndrome has been reported. iNO use for the same has been reported in literature with good response. However, it is practically very difficult to continue iNO in a stable child on a portable ventilator due to problems of scavenging.We report a case of 7-year-old girl who underwent orthotopic liver transplantation (OLT) for severe HPS. Post transplantation the patient had a stormy respiratory course and became severely hypoxemic. She was started on inhaled NO and showed a good response. However, the patient then became NO dependent and multiple attempts to wean iNO failed albeit minimal ventilatory requirements. Following IV L-Arginine infusion, iNO could be weaned within 6 hours without recurrence of hypoxemia. L-Arginine infusion should be considered as a treatment option when facing difficulties to wean iNO in an otherwise well responding patient.en_US
dc.identifier.affiliationsDepartment of Gastroenterology, MM Institute of Medical Sciences (Deemed to be University), Mullana, Ambala, Haryana, Indiaen_US
dc.identifier.affiliationsDepartment of Cardiology, MM Institute of Medical Sciences (Deemed to be University), Mullana, Ambala, Haryana, India.en_US
dc.identifier.affiliationsDepartment of Interventional Cardiology, MM Institute of Medical Sciences (Deemed to be University), Mullana, Ambala, Haryana, India.en_US
dc.identifier.affiliationsDepartment of Cardiology, MM Institute of Medical Sciences (Deemed to be University), Mullana, Ambala, Haryana, India.en_US
dc.identifier.affiliationsDepartment of Cardiology, MM Institute of Medical Sciences (Deemed to be University), Mullana, Ambala, Haryana, India.en_US
dc.identifier.affiliationsDepartment of Cardiology, MM Institute of Medical Sciences (Deemed to be University), Mullana, Ambala, Haryana, India.en_US
dc.identifier.citationKataria Mohnish, Rastogi Abhinav, Manjoor Sajaad, Tanwar Himanshu, Patibandla Sivaji, Singh Vishal V.. Use of L-Arginine for Inhaled Nitric Oxide (iNO) Dependent Hepatopulmonary Syndrome (HPS) Post-Liver Transplant. Journal of Evolution of Medical and Dental Sciences. 2020 Mar; 9(13): 1119-1121en_US
dc.identifier.issn2278-4802
dc.identifier.issn2278-4748
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/214796
dc.languageenen_US
dc.publisherAkshantala Enterprises Private Limiteden_US
dc.relation.issuenumber13en_US
dc.relation.volume9en_US
dc.source.urihttps://dx.doi.org//10.14260/jemds/2020/242en_US
dc.titleUse of L-Arginine for Inhaled Nitric Oxide (iNO) Dependent Hepatopulmonary Syndrome (HPS) Post-Liver Transplanten_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
jemds2020v9n13p1119.pdf
Size:
650.82 KB
Format:
Adobe Portable Document Format
Download
Collections
Journal of Evolution of Medical and Dental Sciences