A comparative analysis of surgical outcome in uveitic and non-uveitic steroid–induced glaucoma in children
dc.contributor.author | Balekudaru, Shantha | en_US |
dc.contributor.author | Shah, Deep | en_US |
dc.contributor.author | Lingam, Vijaya | en_US |
dc.contributor.author | George, Ronnie | en_US |
dc.contributor.author | George, Amala Elizabeth | en_US |
dc.contributor.author | Ganesh, Sudha K | en_US |
dc.contributor.author | Biswas, Jyotirmay | en_US |
dc.contributor.author | Majumder, Parthopratim Dutta | en_US |
dc.contributor.author | Baskaran, Mani | en_US |
dc.date.accessioned | 2023-08-25T06:35:29Z | |
dc.date.available | 2023-08-25T06:35:29Z | |
dc.date.issued | 2022-12 | |
dc.description.abstract | Purpose: To compare outcomes of surgical management of uveitic glaucoma (UG) and steroid?induced glaucoma (SIG) in children in terms of intraocular pressure (IOP) control, visual acuity, and associations for failure. Methods: This was a retrospective case–control study of consecutive UG (cases) and non?uveitic SIG (controls) in children <18 years of age who underwent surgery between January 2005 and December 2017. Results: Primary trabeculectomy with mitomycin C (MMC) was performed in 12 cases (mean age: 9.2 ± 4.3 years) and 40 controls (mean age: 10.4 ± 3.7 years) (P = 0.33). Primary phaco?trabeculectomy with MMC was performed in 11 cases (mean age: 11.4 ± 4.7 years) and 16 controls (mean age: 10.4 ± 3.4 years) (P = 0.57). IOP control (P = 0.26), visual acuity (P = 0.97), number of glaucoma medications (P = 0.06), and survival rates (49% cases vs. 68% controls at 5 years; P = 0.22) were similar between the two groups following trabeculectomy. Survival rates in the phaco?trabeculectomy group at 5 years were 68% cases vs. 69% controls (P = 0.71). IOP was higher (P = 0.008) and visual acuity was worse (P = 0.02) in cases at the last visit. Associations for failure (univariate analysis) were younger age (OR: 6.29, 95% CL: 1.43, 27.67; P = 0.03) and male gender (OR: 4.79, 95% CL: 1.09, 20.97; P = 0.04). On multivariate analysis, younger age (OR: 11.985, 95% CL: 1.071, 134.153; P = 0.04) remained significant. Preoperative number of uveitic attacks was protective on univariate (OR: 0.75, 95% CL: 0.48, 1.15; P = 0.1) and multivariate analyses (OR: 0.49, 95% CL: 0.24, 0.09; P = 0.04). Conclusion: Outcomes of trabeculectomy between cases and controls were similar in our series. However, phaco?trabeculectomy in pediatric uveitic eye group fared worse than eyes with SIG. | en_US |
dc.identifier.affiliations | Smt Jadhavbai Nathamal Singhvee Glaucoma Services, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India | en_US |
dc.identifier.affiliations | Department of Uvea, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India | en_US |
dc.identifier.citation | Balekudaru Shantha, Shah Deep, Lingam Vijaya, George Ronnie, George Amala Elizabeth, Ganesh Sudha K, Biswas Jyotirmay, Majumder Parthopratim Dutta, Baskaran Mani. A comparative analysis of surgical outcome in uveitic and non-uveitic steroid–induced glaucoma in children. Indian Journal of Ophthalmology. 2022 Dec; 70(12): 4218-4225 | en_US |
dc.identifier.issn | 1998-3689 | |
dc.identifier.issn | 0301-4738 | |
dc.identifier.place | India | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/224727 | |
dc.language | en | en_US |
dc.publisher | All India Ophthalmological Society | en_US |
dc.relation.issuenumber | 12 | en_US |
dc.relation.volume | 70 | en_US |
dc.source.uri | https://doi.org/10.4103/ijo.IJO_1475_22 | en_US |
dc.subject | Pediatric uveitic glaucoma | en_US |
dc.subject | phaco?trabeculectomy | en_US |
dc.subject | secondary glaucoma | en_US |
dc.subject | steroid?induced glaucoma | en_US |
dc.subject | trabeculectomy | en_US |
dc.title | A comparative analysis of surgical outcome in uveitic and non-uveitic steroid–induced glaucoma in children | en_US |
dc.type | Journal Article | en_US |
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