Ewing’s sarcoma or peripheral primitive neuroectodermal tumor at the base of tongue: a rare location case report

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dc.contributor.authorDevi, P.en_US
dc.contributor.authorAnjalien_US
dc.contributor.authorYadav, N.en_US
dc.contributor.authorSingh, S.en_US
dc.contributor.authorK. S., Tomer M.en_US
dc.date.accessioned2024-09-24T09:16:04Z
dc.date.available2024-09-24T09:16:04Z
dc.date.issued2023-06
dc.description.abstractPeripheral primitive neuroectodermal tumor now termed as Ewings sarcoma/PNET, representing a family of tumors with varying degrees of neuronal differentiation and genetic rearrangements. Most common sites are extraosseous involving trunk and lower limb. Base of tongue is a very rare site for Ewing’s/PNET, hence in view of rarity of the location as an uncommon presentation, the case has been reported for the better understanding and supporting the literature with the similar finding. A 68 years old female patient presented with the complaint of difficulty in swallowing since 3 months. On examination growth was identified at the left side base of tongue. Biopsy was processed and stained with H&E and other relevant markers. Differentials on the basis microscopic examination were lymphoma, neuroendocrine tumor and primitive neuroectodermal tumor. Various immunohistochemical markers to rule out the given differential were used. The tumor was positive for CD 99 and vimentin. The case was repored as PNET. Peripheral PNET is a challenging topic. Wide range of extraosseous locations have been observed but head and neck being less reported needs to be studied for understanding the behavior of this highly malignant disease in this rare location so that patient can be benefitted by advanced multimodality treatments including surgery, chemotherapy and radiotherapy.en_US
dc.identifier.affiliationsDepartment of Pathology, Pt B. D. Sharma PGIMS, Rohtak, Haryana, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, Pt B. D. Sharma PGIMS, Rohtak, Haryana, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, Pt B. D. Sharma PGIMS, Rohtak, Haryana, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, Pt B. D. Sharma PGIMS, Rohtak, Haryana, Indiaen_US
dc.identifier.affiliationsDepartment of Anaesthesia, Noble Heart Hospital, Rohtak, Haryana, Indiaen_US
dc.identifier.citationDevi P., Anjali, Yadav N., Singh S., K. S. Tomer M.. Ewing’s sarcoma or peripheral primitive neuroectodermal tumor at the base of tongue: a rare location case report. International Journal of Research in Medical Sciences. 2023 Jun; 11(6): 2284-2286en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/233185
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber6en_US
dc.relation.volume11en_US
dc.source.urihttps://doi.org/10.18203/2320-6012.ijrms20231655en_US
dc.subjectPrimitive neuroectodermal tumoren_US
dc.subjectEwing’s sarcomaen_US
dc.subjectExtraosseousen_US
dc.subjectImmunohistochemicalen_US
dc.titleEwing’s sarcoma or peripheral primitive neuroectodermal tumor at the base of tongue: a rare location case reporten_US
dc.typeJournal Articleen_US
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