A comparative study of the clinico-aetiological profile of hyponatremia at presentation with that developing in the hospital

Simple item page
dc.contributor.authorAgarwal, S Mahavir
dc.contributor.authorAgrawal, Aparna
dc.date.accessioned2011-12-07T10:27:13Z
dc.date.available2011-12-07T10:27:13Z
dc.date.issued2011-07
dc.description.abstractBackground & objectives: Hyponatremia is a common problem encountered in patients presenting with nonspecific symptoms. We undertook this study to investigate the clinical profile of patients with hyponatremia, the precipitating factors, the response to therapy and to compare, using these parameters, hyponatremia at presentation to that developing in the hospital. Methods: Seventy consecutive patients with serum sodium less than or equal to 125 mmol/l at presentation or at any time during hospital admission were identified and studied using a proforma. The severity of hyponatremia, therapy given and time taken for recovery were analysed. Results: The mean age of patients was 48.1 ± 16.1 yr. The mean serum sodium was 117.8 ± 6.4 mmol/l. Confusion, headache and malaise were the most common symptoms, two patients had seizures, and 20.0 per cent patients showed no clinical manifestations. Nausea was significantly (P<0.05) more common in patients presenting with hyponatremia. 22 patients (31.4%) developed hyponatremia during their stay in the hospital. 3 patients (4.3%) presented with hyponatremia which got worse during the admission period. Most had multiple precipitating factors, decreased intake being the most common (82.9%), followed by increased losses (65.7%) and miscellaneous factors (70.0%). Drugs, fluid overload and inappropriate Ryle's tube feeds more commonly precipitated hyponatremia in in-hospital patients. Time taken for recovery showed negative correlation with the serum sodium. Patients with in-hospital hyponatremia took significantly longer time to recover (P<0.05). Interpretation & conclusions: Decreased intake was found to be the commonest cause of hyponatremia, thus, ensuring adequate oral intake, especially in patients on liquid diet and in manual labourers, and correction of hyponatremia as soon as an abnormality is detected is important.en_US
dc.identifier.citationAgarwal S Mahavir, Agrawal Aparna. A comparative study of the clinico-aetiological profile of hyponatremia at presentation with that developing in the hospital. Indian Journal of Medical Research. 2011 Jul; 134(1): 118-122.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/135738
dc.language.isoenen_US
dc.source.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171905/en_US
dc.subjectHyponatremiaen_US
dc.subjectin-hospitalen_US
dc.subjectserum sodiumen_US
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshAged, 80 and over
dc.subject.meshConfusion --diagnosis
dc.subject.meshConfusion --etiology
dc.subject.meshFemale
dc.subject.meshHeadache --diagnosis
dc.subject.meshHeadache --etiology
dc.subject.meshHospitalization
dc.subject.meshHumans
dc.subject.meshHyponatremia --diagnosis
dc.subject.meshHyponatremia --drug therapy
dc.subject.meshHyponatremia --etiology
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshNausea --diagnosis
dc.subject.meshNausea --etiology
dc.subject.meshSodium --blood
dc.subject.meshSodium, Dietary --administration & dosage
dc.subject.meshYoung Adult
dc.titleA comparative study of the clinico-aetiological profile of hyponatremia at presentation with that developing in the hospitalen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijmr2011v134n1p118.pdf
Size:
302.03 KB
Format:
Adobe Portable Document Format
Description:
Journal article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Indian Journal of Medical Research