Comparison of the efficacy of ceftibuten and norfloxacin in the treatment of acute gastrointestinal infection in children.

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dc.contributor.authorMoolasart, Pen_US
dc.contributor.authorEampokalap, Ben_US
dc.contributor.authorRatanasrithong, Men_US
dc.date.accessioned2009-05-27T16:23:48Z
dc.date.available2009-05-27T16:23:48Z
dc.date.issued1999-12-06en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractA prospective randomized study was conducted at an infectious disease hospital in Thailand. Ceftibuten was compared with norfloxacin, both given orally for five days for treatment of acute gastroenteritis in children. One hundred and seventy cases were included in the study. Eighty-eight cases were treated with ceftibuten and eighty-two cases with norfloxacin. The baseline characteristics of the patients in both treatment groups were similar. The results showed that mean durations of diarrhea in the ceftibuten and norfloxacin groups were 2.48 days and 2.29 days, respectively, but there was no statistically significant difference between the two groups (p > 0.05). There were Salmonella spp and Shigella spp isolated in both treatment groups and all were susceptible to both antibiotics. The mean durations of Salmonella diarrhea in the ceftibuten and norfloxacin groups were 2.7 and 2.2 days, respectively, while those of Shigella diarrhea were 2.3 days and 2.0 days, respectively. There were no statistically significant differences in either comparison (p > 0.05). Neither complications nor clinical relapses were observed after both antibiotics' treatment.en_US
dc.description.affiliationPediatric Department, Bamrasnaradura Infectious Disease Hospital, Nonthaburi, Thailand. pikulm@health.moph.go.then_US
dc.identifier.citationMoolasart P, Eampokalap B, Ratanasrithong M. Comparison of the efficacy of ceftibuten and norfloxacin in the treatment of acute gastrointestinal infection in children. The Southeast Asian Journal of Tropical Medicine and Public Health. 1999 Dec; 30(4): 764-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/35113
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/1999-30-4/1999-30-4-764.pdfen_US
dc.subject.meshAcute Diseaseen_US
dc.subject.meshAnti-Infective Agents --therapeutic useen_US
dc.subject.meshCephalosporins --therapeutic useen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshDiarrhea --drug therapyen_US
dc.subject.meshDrug Resistance, Microbialen_US
dc.subject.meshDysentery, Bacillary --drug therapyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshNorfloxacin --therapeutic useen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshSalmonella Infections --drug therapyen_US
dc.titleComparison of the efficacy of ceftibuten and norfloxacin in the treatment of acute gastrointestinal infection in children.en_US
dc.typeClinical Trialen_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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