Asymptomatic type B right atrial thrombus in a case with protein S deficiency.
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Date
2014-07
Journal Title
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Abstract
Thirty seven year old asymptomatic male underwent routine medical examination which revealed an abnormal
mass in the right atrium. Family history was not suggestive of any cardiac or malignant disease. Detailed
investigation detected defi ciency of protein S, which is a vitamin K dependent protein and a cofactor for
activated protein C mediated cleavage of factor Va and VIIIa. The defi ciency of protein S predisposes to
venous thrombosis. Further investigation revealed that it was an organized calcifi ed thrombus in right atrium
occupying almost whole of the cavity. Various approaches including surgical excision, thrombolysis and
anticoagulation has been used to manage such thrombosis. However therapeutic approach is still a question
of debate. Atriotomy and excision of mass was done using cardiopulmonary bypass.
Description
Keywords
Cardiopulmonary bypass, Protein S, Thrombus
Citation
Rawat Rajinder Singh, Mehta Yatin, Arora Dheeraj, Trehan Naresh. Asymptomatic type B right atrial thrombus in a case with protein S deficiency. Annals of Cardiac Anaesthesia. 2014 Jul; 17(3): 237-239.