Bisphosphonate induced necrosis of jaws-the emerging challenging epidemic
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Date
2025-02
Journal Title
Journal ISSN
Volume Title
Publisher
Scholars Publisher
Abstract
Background: The bisphosphonates are widely prescribed drugs to prevent bone resorption, however, are associated with the potential risk of osteonecrosis of jaws in patients receiving dental treatment. Methods: The study was designed to evaluate the chances of osteonecrosis in patients referred for management in whom dental treatment was carried out of negligence or lack of knowledge. Results: Out of 74 patients studied, 16 patients had developed osteonecrosis, particularly after dental extraction, and out of 16 patients, 12 patients were having underlying malignancy. Conclusion: Medication-induced necrosis of jaws is more in patients with underlying malignancy or other comorbidities compared to patients who are not suffering from malignancy, and dental treatment particularly extraction is a trigger in such patients for developing the debilitating condition.
Description
Keywords
Bisphosphonates, MRONJ, osteonecrosis.
Citation
Malik Altaf Hussain, Vaishnov Kalpesh, Majeed Shabnum, Sheikh Tafazul, Shah Altaf H. . Bisphosphonate induced necrosis of jaws-the emerging challenging epidemic. Annals of International Medical and Dental Research. 2025 Feb; 11(1): 40-43