Skeletal angiomatosis - rare cause of bone destruction: a case report with review of literature.

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dc.contributor.authorMalik, Reenien_US
dc.contributor.authorMalik, Rajeshen_US
dc.contributor.authorTandon, Suneeten_US
dc.contributor.authorTandon, Puneeten_US
dc.date.accessioned2008-10-15en_US
dc.date.accessioned2009-05-29T11:02:21Z
dc.date.available2008-10-15en_US
dc.date.available2009-05-29T11:02:21Z
dc.date.issued2008-10-15en_US
dc.description25 references.en_US
dc.description.abstractClassification of skeletal angiomatosis into aggressive and nonaggressive types is on the basis of their clinical behavior and pattern of skeletal involvement (regional and disseminated). Gorham's disease (massive osteolysis) is an aggressive form of skeletal angiomatosis that shows regional involvement, frequently involving the shoulder and hip areas. Cystic angiomatosis is a nonaggressive form of skeletal angiomatosis with multifocal involvement, predominantly affecting the trunk bones. The imaging modalities gave the diagnosis of cystic angiomatosis of humerus showing multicystic lytic areas. The histopathological differential diagnosis was cystic angiomatosis and Gorham's disease, as microscopically both are indistinguishable from each other. Both represent a complex network of dilated thin-walled capillaries growing in the marrow space associated with the destruction of bone and infiltration into the adjacent soft tissues. The case is presented because of its extreme rarity and due to the diagnostic dilemma, whether to label it as Gorham's disease or as cystic angiomatosis. Considering the site involved and its aggressiveness, the diagnosis is in favor of Gorham's vanishing bone disease as cystic angiomatosis is multicentric and nonaggressive, involving mostly vertebrae and skull with multicystic lytic lesions.en_US
dc.description.affiliationDepartment of Pathology, Gandhi Medical College, Bhopal, India. reenimalik@yahoo.co.inen_US
dc.identifier.citationMalik R, Malik R, Tandon S, Tandon P. Skeletal angiomatosis - rare cause of bone destruction: a case report with review of literature. Indian Journal of Pathology & Microbiology. 2008 Oct-Dec; 51(4): 515-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/73083
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAngiomatosis --diagnosisen_US
dc.subject.meshBone Cysts --diagnosisen_US
dc.subject.meshBone Diseases --diagnosisen_US
dc.subject.meshChilden_US
dc.subject.meshDiagnosis, Differentialen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshHumerus --pathologyen_US
dc.subject.meshOsteolysis, Essential --diagnosisen_US
dc.titleSkeletal angiomatosis - rare cause of bone destruction: a case report with review of literature.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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