Interstitial Lung Disease in Rheumatoid Arthritis: A Prospective Study at a Tertiary Care Center

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dc.contributor.authorOak, Jen_US
dc.contributor.authorSharma, Sen_US
dc.contributor.authorShastri, Ren_US
dc.contributor.authorSingh, S.en_US
dc.date.accessioned2023-08-09T06:06:27Z
dc.date.available2023-08-09T06:06:27Z
dc.date.issued2022-09
dc.description.abstractObjective: The objective of this study was to evaluate the presence of interstitial lung disease (ILD) in rheumatoid arthritis (RA) and to determine the role of clinical, spirometry, and high-resolution computed tomography (HRCT) findings to facilitate early detection of ILD in RA. Materials and methods: This is a prospective study at a tertiary care hospital from February 2016 to June 2019. All patients satisfying the American College of Rheumatology (ACR) criteria for RA and having respiratory symptoms or signs were included. All patients had detailed history, clinical examination, laboratory evaluation, spirometry, and HRCT chest. Results: A total of 280 patients of RA with respiratory symptoms were evaluated, out of which 82 (29.29%) had pulmonary involvement. There were 70 women and 12 men. Rheumatoid factor was positive in 90.2% of patients while anti-CCP antibody was positive in 43.9%. Chest X-ray (CXR) showed bilateral haziness in 36.9%. HRCT findings revealed a usual interstitial pneumonia (UIP) pattern in 73.2% patients and 24% had an nonspecific interstitial pneumonia (NSIP) pattern. Spirometric evidence of lung involvement was present in 84.2% of these cases. 2D Echo showed pulmonary hypertension (PH) in 46.3% of patients. Conclusion: Screening for respiratory symptoms and signs is essential in the clinical evaluation of RA. CXR, HCRT chest, and spirometry can be used effectively to diagnose RA-ILD early.en_US
dc.identifier.affiliationsDepartment of Medicine and Rheumatology, Kokilaben Dhirubhai Ambani Hospital, Four Bungalows, Achutrao Patwardhan Marg, Andheri West, Mumbai, Maharashtra, Indiaen_US
dc.identifier.citationOak J, Sharma S, Shastri R, Singh S.. Interstitial Lung Disease in Rheumatoid Arthritis: A Prospective Study at a Tertiary Care Center. Indian Journal of Chest Diseases & Allied Sciences. 2022 Sep; 64(3): 168-172en_US
dc.identifier.issn0377-9343
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/221816
dc.languageenen_US
dc.publisherJaypee Brothers Medical Publishers Pvt. Ltden_US
dc.relation.issuenumber3en_US
dc.relation.volume64en_US
dc.source.urihttps://doi.org/10.5005/jp-journals-11007-0051en_US
dc.subjectHigh-resolution computed tomographyen_US
dc.subjectInterstitial lung diseaseen_US
dc.subjectNonspecific interstitial pneumoniaen_US
dc.subjectRheumatoid arthritisen_US
dc.subjectSpirometryen_US
dc.subjectUsual interstitial pneumoniaen_US
dc.titleInterstitial Lung Disease in Rheumatoid Arthritis: A Prospective Study at a Tertiary Care Centeren_US
dc.typeJournal Articleen_US
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