Dyslipidaemia in elderly and stroke patients

dc.contributor.authorKahali, Dhimanen_US
dc.date.accessioned2025-05-09T07:17:53Z
dc.date.available2025-05-09T07:17:53Z
dc.date.issued2024-03
dc.description.abstractLowering of cholesterol containing atherogenic particles through lipid lowering therapies is of outmost important in both in the elderly age group and younger age group in reducing the cardiovascular risk. This chapter sum- marizes the current existing knowledge regarding the factors which affects the key decision-making process in patients with older age, and also in special circumstance where the direct evidence of benefit for cholesterol lowering is lacking. Effort has been made to briefly summarize the recommendations to the patient and his/her family based on risk stratification of atherosclerotic versus non-atherosclerotic cardiovascular disease, comor- bidity burden, quality of life, survival prognosis, lifestyle/socioeconomic status and presence of frailty. Here in this chapter, we have collated and presented the available robust clinical trial evidence which is very much necessary for the assessment of risk versus benefit for hypolipidemic drugs in the elderly age group. While plethora of pharmacological interventions has evolved including statins, ezetimibe, bempedoic acid, PCSK9 inhibitors, Inclisiran etc., but it is essential to establish lipid-lowering therapy goals based on the stroke subtype and the presence of comorbidities. Here in this section we have reviewed the collated clinical evidences for optimal drug regimen recommendation for elderly stroke patients for both primary and secondary prevention.en_US
dc.identifier.affiliationsBM Birla Heart Institute, Kolkata, West Bengal, Indiaen_US
dc.identifier.citationKahali Dhiman . Dyslipidaemia in elderly and stroke patients. Indian Heart Journal. 2024 Mar; 76(1): 75-79en_US
dc.identifier.issn0019-4832
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/242770
dc.languageenen_US
dc.publisherElsevieren_US
dc.relation.issuenumber1en_US
dc.relation.volume76en_US
dc.source.urihttps://doi.org/10.1016/j.ihj.2024.01.013en_US
dc.subjectDyslipidemiaen_US
dc.subjectElderlyen_US
dc.subjectStrokeen_US
dc.subjectStatinen_US
dc.subjectPreventionen_US
dc.titleDyslipidaemia in elderly and stroke patientsen_US
dc.typeJournal Articleen_US
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