Chronic kidney disease in pregnancy and fetomaternal outcome

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dc.contributor.authorGupta, Poojaen_US
dc.contributor.authorChawla, Induen_US
dc.contributor.authorAra, Anjumen_US
dc.contributor.authorMalik, Renukaen_US
dc.date.accessioned2020-10-16T07:58:40Z
dc.date.available2020-10-16T07:58:40Z
dc.date.issued2019-09
dc.description.abstractBackground: Chronic kidney disease is a heterogeneous group of renal dysfunctions with complex and varied presentations in pregnancy. With a long asymptomatic course, timely diagnosis and management is crucial for fetomaternal wellbeing.Methods: A retrospective cohort study over a period of 3 years and 4 months included all obstetric in patients with known or newly diagnosed renal disorders. Maternal outcome was measured with regard to biochemical parameters presence /absence of proteinuria, hypertension, mode of pregnancy termination and complications. Fetal outcome was noted with respect to antenatal complications, weight, Apgar, NICU stay. Computation of results was done using percentages, mean and proportions.Results: Out of 13 women studied, 53.8% were pre-diagnosed cases of renal dysfunction and 46.2% were diagnosed during pregnancy. 38% had proteinuria at first visit and 50% remained so even after delivery. 60% had history of pregnancy induced hypertension in their previous pregnancies. Secondary hypertension and superimposed preeclampsia were seen in 30% and 38% cases respectively, with only one patient requiring magnesium sulphate prophylaxis in post-partum. Cardiac dysfunction was found to be coexisting in 15.3% cases with pre-existing renal leision. Intrauterine growth restriction was seen in 61.5% cases Average fetal weight was 2. 26kg with 30% having NICU stay. 30.6% had preterm delivery. Mode of delivery was caesarean section in 46% cases.Conclusions: Pregnancy with CKD is a high-risk pregnancy with adverse fetomaternal outcomes. For optimal pregnancy outcomes, an expert multidisciplinary team is required. With limited studies in south Asian population, there needs to be an upgradation in registry system.en_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynecology, PGIMER and Dr. R. M. L. Hospital, New Delhi, Indiaen_US
dc.identifier.citationGupta Pooja, Chawla Indu, Ara Anjum, Malik Renuka. Chronic kidney disease in pregnancy and fetomaternal outcome. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2019 Sep; 8(9): 3518-3523en_US
dc.identifier.issn2320-1770
dc.identifier.issn2320-1789
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/207001
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber9en_US
dc.relation.volume8en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-1770.ijrcog20193769en_US
dc.subjectAcute kidney failureen_US
dc.subjectCardiac failureen_US
dc.subjectObstetric nephrologyen_US
dc.subjectPregnancyen_US
dc.subjectPrematureen_US
dc.subjectStillbirthen_US
dc.titleChronic kidney disease in pregnancy and fetomaternal outcomeen_US
dc.typeJournal Articleen_US
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