BinaxNOW® - An immunochromatographic test for the diagnosis of human influenza viruses: Comparison with viral culture and polymerase chain reaction.

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dc.contributor.authorBhattacharya, S
dc.contributor.authorOsman, H
dc.date.accessioned2012-12-11T07:58:55Z
dc.date.available2012-12-11T07:58:55Z
dc.date.issued2011-01
dc.description.abstractPurpose: A rapid test for influenza viruses (Binax NOW® ) was evaluated. Materials and Methods: In season-1, 35 respiratory samples were tested retrospectively; in season-2, 45 samples were tested prospectively [gold-standard: viral culture in season-1, culture+ reverse transcriptase-polymerase chain reaction (RT-PCR) in season-2]. Results: Sensitivity for Binax for influenza A was 59.3 and 0% in season-1 and -2, respectively. Sensitivity was low for influenza B (33.3% in season-1, 26.1% in season-2). Samples having low viral load were more likely to have a negative Binax test. Specificity of Binax was high (100 and 94.7% with influenza A and B, respectively). Conclusion: Sensitivity information provided in the kit insert does not always reflect post licensure performance in clinical settings.en_US
dc.identifier.citationBhattacharya S, Osman H. BinaxNOW® - An immunochromatographic test for the diagnosis of human influenza viruses: Comparison with viral culture and polymerase chain reaction. Indian Journal of Medical Microbiology. 2011 Jan-Mar; 29(1): 19-21.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/143769
dc.language.isoenen_US
dc.source.urihttps://www.ijmm.org/article.asp?issn=0255-0857;year=2011;volume=29;issue=1;spage=19;epage=21;aulast=Bhattacharyaen_US
dc.subjectInfluenzaen_US
dc.subjectrapid antigen testen_US
dc.subjectsensitivityen_US
dc.subject.meshClinical Laboratory Techniques --methods
dc.subject.meshHumans
dc.subject.meshImmunoassay --methods
dc.subject.meshInfluenza, Human --diagnosis
dc.subject.meshInfluenza, Human --virology
dc.subject.meshOrthomyxoviridae --classification
dc.subject.meshOrthomyxoviridae --isolation & purification
dc.subject.meshPolymerase Chain Reaction --methods
dc.subject.meshReagent Kits, Diagnostic
dc.subject.meshSensitivity and Specificity
dc.subject.meshTime Factors
dc.subject.meshVirology --methods
dc.subject.meshVirus Cultivation --methods
dc.titleBinaxNOW® - An immunochromatographic test for the diagnosis of human influenza viruses: Comparison with viral culture and polymerase chain reaction.en_US
dc.typeArticleen_US
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