Arthritis in children: an occult manifestation of Bancroftian filariasis.

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dc.contributor.authorChaturvedi, Pen_US
dc.contributor.authorGawdi, A Men_US
dc.contributor.authorParkhe, Ken_US
dc.contributor.authorHarinath, B Cen_US
dc.contributor.authorDey, S Ken_US
dc.date.accessioned1993-11-01en_US
dc.date.accessioned2009-05-30T15:33:53Z
dc.date.available1993-11-01en_US
dc.date.available2009-05-30T15:33:53Z
dc.date.issued1993-11-01en_US
dc.description.abstractA form of unexplained arthritis, not attributable to known causes, seen in children (0-14 yrs) in this endemic zone of Bancroftian filariasis was investigated for its association with filariasis. Nineteen cases of undiagnosed arthritis were screened for filarial IgG antibodies to Wuchereria by Stick Enzyme Linked Immunosorbent Assay (ELISA). All had large joint involvement, the commonest joint affected being the knee joint. Involvement was monoarticular in 10 and binarticular in 9. Joint pain was present in 18 and effusion in 12. Five patients had recurrent episodes. Sixteen (84.2%) showed filarial antibodies of which only one (5.3%) was microfilaraemic. Patients with classical filariasis (16), disease controls (10), endemic normals (15) and non-endemic normals (10) were also subjected to ELISA to ascertain the sensitivity and specificity of the technique. Fifteen (93.8%) cases of classical filariasis and 1 (6.7%) of endemic normal were antibody positive, whereas none of disease controls and non-endemic normals had filarial antibodies. Nine cases of filarial arthritis reviewed after a course of Diethylcarbamazine showed satisfactory response to treatment.en_US
dc.description.affiliationDepartment of Pediatrics, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha.en_US
dc.identifier.citationChaturvedi P, Gawdi AM, Parkhe K, Harinath BC, Dey SK. Arthritis in children: an occult manifestation of Bancroftian filariasis. Indian Journal of Pediatrics. 1993 Nov-Dec; 60(6): 803-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/83738
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/icb/icbai.shtmlen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAnimalsen_US
dc.subject.meshArthritis, Infectious --diagnosisen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshDeveloping Countriesen_US
dc.subject.meshDiagnosis, Differentialen_US
dc.subject.meshDiethylcarbamazine --therapeutic useen_US
dc.subject.meshElephantiasis, Filarial --diagnosisen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshWuchereria bancrofti --drug effectsen_US
dc.titleArthritis in children: an occult manifestation of Bancroftian filariasis.en_US
dc.typeJournal Articleen_US
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