Schwannoma-like pleomorphic adenoma: A pathological quandary
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Date
2025-03
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Publisher
Wolters Kluwer - Medknow
Abstract
Pleomorphic adenoma usually presents as a painless growing mass in locations of the salivary glands and is notorious for local recurrence if previous surgical resection is incomplete. Schwannoma is a benign peripheral nerve tumor with microscopic features of sheets of spindle?shaped cells with nuclear palisading. However, when a pathologist encounters a salivary gland tumor with microscopic morphological features of biphasic components with areas of schwannoma?like morphology, it is crucial to make a prudent diagnosis by differentiating Schwannoma?like pleomorphic adenoma and its differential diagnosis as they have remarkably different outcome in patients. We herein present a case of Schwannoma?like pleomorphic adenoma and discuss its approach to diagnosis and literature search.
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Keywords
Pleomorphic adenoma, Schwannoma like pleomorphic adenoma, Immunihistochemistry in Pleomorphic adenoma
Citation
Gautam R, Tomar R, Rana D, Khurana N, Singh I. Schwannoma-like pleomorphic adenoma: A pathological quandary. Indian Journal of Pathology & Microbiology. 2025 Mar; 68(1): 168-170