Serum Electrolytes and Red Blood Cell Membrane Potential of Hypertensive Patients

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dc.contributor.authorConstance, Nwadikeen_US
dc.contributor.authorIjeoma, Nosiri Chidien_US
dc.contributor.authorAdindu, Ezeen_US
dc.contributor.authorChimaraoke, Onyeaboen_US
dc.contributor.authorSunday, Ezekwe Ahamefulaen_US
dc.contributor.authorCatherine, Onyejiekween_US
dc.date.accessioned2020-04-09T05:43:27Z
dc.date.available2020-04-09T05:43:27Z
dc.date.issued2019
dc.description.abstractSerum electrolyte and red blood cell membrane potential of hypertensive patients in Owerri metropolis were investigated. A total of 50 volunteer subjects were used for the study. Thirty (30) of the volunteer subjects were hypertensive subjects and were used as test subjects; while the remaining 20 subjects were healthy subjects with normal blood pressure used as normentensive subjects (control). Results observed showed increased red blood cell (RBC) K+ and Cl- in hypertension subjects against normentensive subjects. Apart from K+ which reduced significantly (p<0.05), other electrolyte ions of the serum increased significantly (p<0.05) in hypertensive subjects against normentensive subjects. However, Na+ and Cl- membrane potential was not significantly (p>0.05) altered in hypertensive subjects against normotensive subjects while K+ was significantly (p<0.05) altered. The observed alterations in the parameters investigated in hypertensive subjects in the present study could be as a result of a host of derangements involving electrolyte metabolism, altered membrane transport and a possible increase in membrane fragility. This study has shown the serum electrolyte and red blood cell membrane potential of hypertensive patients in Owerri metropolis.en_US
dc.identifier.affiliationsDepartment of Medical Laboratory Science, Imo State University, Owerri, Nigeria.en_US
dc.identifier.affiliationsDepartment of Biochemistry, Abia State University, Uturu, Nigeria.en_US
dc.identifier.affiliationsDepartment of Biochemistry, University of Calabar, Calabar, Nigeria.en_US
dc.identifier.affiliationsDepartment of Biochemistry, Michael Okpara University of Agriculture, Umudike, Nigeria.en_US
dc.identifier.affiliationsDepartment of Medical Biochemistry, Imo State University, Owerri, Nigeria.en_US
dc.identifier.affiliationsDepartment of Biochemistry, University of Lagos, Nigeria.en_US
dc.identifier.citationConstance Nwadike, Ijeoma Nosiri Chidi, Adindu Eze, Chimaraoke Onyeabo, Sunday Ezekwe Ahamefula, Catherine Onyejiekwe. Serum Electrolytes and Red Blood Cell Membrane Potential of Hypertensive Patients. International Blood Research & Reviews. 2019; 10(1): 1-7en_US
dc.identifier.issn2321-7219
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/192760
dc.languageenen_US
dc.publisherInternational Blood Research & Reviewsen_US
dc.relation.issuenumber1en_US
dc.relation.volume10en_US
dc.source.urihttps://doi.org/10.9734/ibrr/2019/v10i130110en_US
dc.subjectElectrolyteen_US
dc.subjecthypertensive patientsen_US
dc.subjectmembrane potentialen_US
dc.subjectred blood cellen_US
dc.titleSerum Electrolytes and Red Blood Cell Membrane Potential of Hypertensive Patientsen_US
dc.typeJournal Articleen_US
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