Clinical trial to determine the antidiarrhoeal potential of traditional medicine formulations TMFs-16, TMF-35a and TMF-43

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dc.contributor.authorThaw Zinen_US
dc.contributor.authorMay Aye Thanen_US
dc.contributor.authorTin Tin Layen_US
dc.contributor.authorCho Choen_US
dc.contributor.authorTin Ohnen_US
dc.contributor.authorTin Mi Mi Naingen_US
dc.contributor.authorWin Khineen_US
dc.contributor.authorMaung Maung Winten_US
dc.date.accessioned2009-06-30T08:57:01Z
dc.date.available2009-06-30T08:57:01Z
dc.date.created1994-12-01en_US
dc.date.issued1994-12-01en_US
dc.description.abstractClinical trial to determine the therapeutic efficacy of three Traditional Medicine Formulations, claimed to have antidiarrhoeal action, were studied on 150 acute diarrhoeal patients admitted to the Infectious Diseases Hospital, Yangon. TMF-16 was found to possess a good antidiarrhoeal action with the antidiarrhoeal index (ADI) of 28.71 percent, which is approximately equal to that of the standard drug, loparamide which had the ADI of 27.94 percent. TMF-35a also possess a mild to moderate antidiarrhoeal action (ADI = 21.5 percent), but TMF-43 showed little or no antidiarrhoeal action (ADI = 9.64 percent). The cllinical significance of the study is that both TMF-16 and loparamide were found to reduce the stool output as well as the amount of fluid replacement required. TMF-16 is well tolerated, available locally and cheaply, and thus, may prove beneficial in the symptomatic relief of non-specific acute diarrhoea.en_US
dc.identifier.citationThaw Zin, May Aye Than, Tin Tin Lay, Cho Cho, Tin Ohn, Tin Mi Mi Naing, Win Khine, Maung Maung Wint. Clinical trial to determine the antidiarrhoeal potential of traditional medicine formulations TMFs-16, TMF-35a and TMF-43. Myanmar Health Sciences Research Journal. 1994; 6(3): 127-132en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/127024
dc.subject.meshClinical Trialsen_US
dc.subject.meshFormulariesen_US
dc.subject.meshAntidiarrhealsen_US
dc.subject.meshMedicine, Myanmar Traditionalen_US
dc.subject.meshMyanmaren_US
dc.titleClinical trial to determine the antidiarrhoeal potential of traditional medicine formulations TMFs-16, TMF-35a and TMF-43en_US
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