Multidisciplinary studies of disease burden in the Diseases of the Most Impoverished Programme.

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dc.contributor.authorDeen, Jacqueline Len_US
dc.contributor.authorvon Seidlein, Lorenzen_US
dc.contributor.authorClemens, John Den_US
dc.date.accessioned2004-09-22en_US
dc.date.accessioned2009-05-27T03:49:44Z
dc.date.available2004-09-22en_US
dc.date.available2009-05-27T03:49:44Z
dc.date.issued2004-09-22en_US
dc.descriptionJournal of Health, Population, and Nutrition.en_US
dc.description.abstractWith limited healthcare resources, rational prioritization of healthcare interventions requires knowledge and analysis of disease burden. In the absence of actual disease-burden data from less-developed countries, various types of morbidity and mortality estimates have been made. Besides having questionable reliability, these estimates do not capture the full burden of a disease since they provide only the number of cases and deaths. The modelling methods that include disability are more comprehensive but are difficult to understand, and their reliability is affected by baseline approximations. To provide policy-makers with information needed for rational decision-making, the Diseases of the Most Impoverished (DOMI) Programme of the International Vaccine Institute has used a multidisciplinary approach to describe the burden of disease due to typhoid fever, shigellosis, and cholera. Recognizing the relative advantages and disadvantages of various methodologies, the programme employs passive clinic-based surveillance in defined communities to provide prospective data. The prospective data are complemented with retrospectively-collected information from existing sources, frequently less accurate and complete but readily available for the whole population over extended periods. To create a more complete picture, economic and qualitative studies specific to each disease are incorporated in these prospective studies. The goal is to achieve a more complete and realistic picture by combining the results of these various methodologies, acknowledging the strengths and limitations of each. These projects also build in-country capacity in terms of treatment, diagnosis, epidemiology, and data management.en_US
dc.description.affiliationInternational Vaccine Institute, Seoul 151-600, Republic of Korea. jdeen@ivi.inten_US
dc.identifier.citationDeen JL, von Seidlein L, Clemens JD. Multidisciplinary studies of disease burden in the Diseases of the Most Impoverished Programme. Journal of Health, Population, and Nutrition. 2004 Sep; 22(3): 232-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/657
dc.language.isoengen_US
dc.source.urihttps://www.icddrb.org/pub/publication.jsp?classificationID=30&typeClassificationID=2en_US
dc.source.urihttps://www.icddrb.org/publication.cfm?classificationID=30&pubID=5625en_US
dc.subject.meshCholera --mortalityen_US
dc.subject.meshCost of Illnessen_US
dc.subject.meshDeveloping Countriesen_US
dc.subject.meshDysentery, Bacillary --mortalityen_US
dc.subject.meshHealth Surveysen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunization Programs --organization & administrationen_US
dc.subject.meshPovertyen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshTyphoid Fever --mortalityen_US
dc.subject.meshVaccination --methodsen_US
dc.titleMultidisciplinary studies of disease burden in the Diseases of the Most Impoverished Programme.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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