Statin The Most Controversial Drug Of Our Times: A Commentary

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dc.contributor.authorSrivastava, Mrinal Ranjanen_US
dc.contributor.authorChandra, Anuen_US
dc.date.accessioned2019-11-16T07:21:19Z
dc.date.available2019-11-16T07:21:19Z
dc.date.issued2017-01
dc.description.abstractCardiovascular disease (CVD) is the leading cause of death worldwide.Atheroscelerotic cardiovascular disease(ASCVD) is also a leading cause of death and disability. Statins can reduce the risk and prevent heart diseases. One of the best studied medication and in randomized controlled trials have been proven to reduce the no of Heart attacks and stroke even in individuals with normal cholesterol levels. A small no of individuals may develop Diabetes on statins.The benefit from lowering the risk of death, heart attack and stroke are likely to outweigh the development of diabetes in those individuals. The beneficial effects of statins may not only be due to the cholesterol lowering effects but also due to cholesterol independent or pleiotropic effects. These benefits include endothelial protective functions, enhancing stability of atherosclerotic plaques and inhibiting vascular smooth muscle proliferation and platelet aggregation. It remains to be seen to what extent these pleiotropic benefits of statin therapy can be attributed beyond cholesterol lowering.en_US
dc.identifier.affiliationsDepartment of Community Medicine, Era's Lucknow Medical College & Hospital Sarfarazganj, Lucknow, U.P., India.-226003en_US
dc.identifier.affiliationsDepartment of Biochemistry, Era's Lucknow Medical College & Hospital Sarfarazganj, Lucknow, U.P., India.-226003en_US
dc.identifier.citationSrivastava Mrinal Ranjan, Chandra Anu. Statin The Most Controversial Drug Of Our Times: A Commentary. Era's Journal of Medical Research. 2017 Jan-Jun; 4(1): 43-46en_US
dc.identifier.issn2348-9839
dc.identifier.issn2394-5222
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/183970
dc.languageenen_US
dc.publisherEra's Lucknow Medical College and Hospitalen_US
dc.relation.issuenumber1en_US
dc.relation.volume4en_US
dc.subjectStatinsen_US
dc.subjectCardiovascular Diseaseen_US
dc.subjectDyslipidemiaen_US
dc.subjectAtheroscelerosisen_US
dc.subjectCholesterolen_US
dc.titleStatin The Most Controversial Drug Of Our Times: A Commentaryen_US
dc.typeJournal Articleen_US
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