Measurements of urinary state of saturation with respect to calcium oxalate and brushite (CaHPO4.2H2O) in renal stone formers.

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dc.contributor.authorSriboonlue, Pen_US
dc.contributor.authorPrasongwattana, Ven_US
dc.contributor.authorTungsanga, Ken_US
dc.contributor.authorSitprija, Ven_US
dc.date.accessioned2009-05-27T19:04:37Z
dc.date.available2009-05-27T19:04:37Z
dc.date.issued1990-12-01en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractUrinary supersaturation with respect to calcium oxalate and/or brushite (CaHPO4.2H2O) is critical for the formation of calcium stones. The aim of this study is to use concentration product ratio (CPR) as a tool to assess the state of urine saturation with respect to calcium oxalate and brushite. One 24-h urine specimen from each of 16 healthy city dwellers (GI), 18 healthy villagers (GII) and 28 villagers with renal stones (GIII) was collected and analyzed for calcium, sodium, potassium, phosphate, uric acid, citrate and oxalate. The CPRs of calcium and oxalate and of calcium and phosphate before and after equilibration of the urine with the corresponding seeding crystals were also determined. Urinary volume and the excretion rate of calcium, potassium, uric acid, citrate and oxalate of GII and of sodium, phosphate, uric acid and citrate of GIII were significantly less than those of GI. The CPRs for calcium oxalate and brushite were 2.9 +/- 0.3 and 1.7 +/- 0.2 for GI, 2.7 +/- 0.2 and 1.3 +/- 0.1 for GII and 2.5 +/- 0.2 and 1.1 +/- 0.1 for GIII, respectively. The CPR values indicated that urine of all groups was generally supersaturated with respect to calcium oxalate salt (CPRs were above 1) and were not different among the groups. With regard to brushite, urine was also supersaturated but the state of supersaturation was less than that of calcium oxalate. Furthermore, instead of being supersaturated, brushite in many urine specimens of GIII was undersaturated and its mean CPR was even significantly less than that of GI (P less than 0.01).en_US
dc.description.affiliationDepartment of Biochemistry, Faculty of Medicine, Khon Kean University, Thailand.en_US
dc.identifier.citationSriboonlue P, Prasongwattana V, Tungsanga K, Sitprija V. Measurements of urinary state of saturation with respect to calcium oxalate and brushite (CaHPO4.2H2O) in renal stone formers. Journal of the Medical Association of Thailand. 1990 Dec; 73(12): 684-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/40423
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdulten_US
dc.subject.meshCalcium Oxalate --urineen_US
dc.subject.meshCalcium Phosphates --urineen_US
dc.subject.meshHumansen_US
dc.subject.meshKidney Calculi --urineen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPhosphates --urineen_US
dc.subject.meshThailanden_US
dc.titleMeasurements of urinary state of saturation with respect to calcium oxalate and brushite (CaHPO4.2H2O) in renal stone formers.en_US
dc.typeJournal Articleen_US
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