Falciparum malaria--present day problems. An experience with 425 cases.
dc.contributor.author | Mehta, S R | en_US |
dc.contributor.author | Naidu, G | en_US |
dc.contributor.author | Chandar, V | en_US |
dc.contributor.author | Singh, I P | en_US |
dc.contributor.author | Johri, S | en_US |
dc.contributor.author | Ahuja, R C | en_US |
dc.date.accessioned | 1989-04-01 | en_US |
dc.date.accessioned | 2009-05-30T18:56:31Z | |
dc.date.available | 1989-04-01 | en_US |
dc.date.available | 2009-05-30T18:56:31Z | |
dc.date.issued | 1989-04-01 | en_US |
dc.description.abstract | Clinical details and present day problems encountered in 425 cases of falciparum malaria (PF) are reported. 10.11% had taken chloroquine prior to reporting to us. Parasitic count done in 23.05% cases lacked correlation with severity of disease. Pattern of fever varied markedly but 5.4% were afebrile throughout and presented only with bodyache and malaise. Apyrexial spell was noted in 5.64%. 28.70% had typical facial looks of anaemia and sallow complexion. Cerebral symptoms were noted in 3.05%. Other symptoms were severe headache 33.4%, pain abdomen 3.29%, gastroenteritis 5.64%, jaundice 2.58% and bronchitis in 7.50%. We encountered subconjunctival haemorrhages with purpura and/or urticaria in four cases, symptoms suggestive of shock lung in 3, pulmonary oedema in 2, severe anaemia (HB less than 4 g%) in seven pregnant ladies, extrapyramidal symptoms in follow up period in 5 and congenital malaria in 2 cases. 83.25% were cured with chloroquine and oxytetracycline. 8.47% (who deteriorated despite the above treatment) were treated with quinine for 6 days. 5.17% (with severe disease) were also given quinine as first line drug. 2.82% (unresponsive to chloroquine and oxytetracycline but with mild disease) were treated with pyrimethamine-sulphamezathine combination for 5 days. One case who did not respond to quinine was treated with quinidine. Recrudescence was seen in 3.67% of patients treated with chloroquine and oxytetracycline. There was no case with renal failure, haemolysis due to G6PD deficiency and black water fever. There was only one death (0.23%) in our series. Self-medication, haphazard therapy and the slogan "Fever may be malaria-take chloroquine" can lead to problems in falciparum malaria. | en_US |
dc.identifier.citation | Mehta SR, Naidu G, Chandar V, Singh IP, Johri S, Ahuja RC. Falciparum malaria--present day problems. An experience with 425 cases. Journal of the Association of Physicians of India. 1989 Apr; 37(4): 264-7 | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/86312 | |
dc.language.iso | eng | en_US |
dc.source.uri | https://www.japi.org | en_US |
dc.subject.mesh | Adolescent | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Aged | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Child | en_US |
dc.subject.mesh | Child, Preschool | en_US |
dc.subject.mesh | Chloroquine --therapeutic use | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | India | en_US |
dc.subject.mesh | Infant | en_US |
dc.subject.mesh | Infant, Newborn | en_US |
dc.subject.mesh | Malaria --drug therapy | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Oxytetracycline --therapeutic use | en_US |
dc.subject.mesh | Plasmodium falciparum | en_US |
dc.title | Falciparum malaria--present day problems. An experience with 425 cases. | en_US |
dc.type | Journal Article | en_US |
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