Falciparum malaria--present day problems. An experience with 425 cases.

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dc.contributor.authorMehta, S Ren_US
dc.contributor.authorNaidu, Gen_US
dc.contributor.authorChandar, Ven_US
dc.contributor.authorSingh, I Pen_US
dc.contributor.authorJohri, Sen_US
dc.contributor.authorAhuja, R Cen_US
dc.date.accessioned1989-04-01en_US
dc.date.accessioned2009-05-30T18:56:31Z
dc.date.available1989-04-01en_US
dc.date.available2009-05-30T18:56:31Z
dc.date.issued1989-04-01en_US
dc.description.abstractClinical details and present day problems encountered in 425 cases of falciparum malaria (PF) are reported. 10.11% had taken chloroquine prior to reporting to us. Parasitic count done in 23.05% cases lacked correlation with severity of disease. Pattern of fever varied markedly but 5.4% were afebrile throughout and presented only with bodyache and malaise. Apyrexial spell was noted in 5.64%. 28.70% had typical facial looks of anaemia and sallow complexion. Cerebral symptoms were noted in 3.05%. Other symptoms were severe headache 33.4%, pain abdomen 3.29%, gastroenteritis 5.64%, jaundice 2.58% and bronchitis in 7.50%. We encountered subconjunctival haemorrhages with purpura and/or urticaria in four cases, symptoms suggestive of shock lung in 3, pulmonary oedema in 2, severe anaemia (HB less than 4 g%) in seven pregnant ladies, extrapyramidal symptoms in follow up period in 5 and congenital malaria in 2 cases. 83.25% were cured with chloroquine and oxytetracycline. 8.47% (who deteriorated despite the above treatment) were treated with quinine for 6 days. 5.17% (with severe disease) were also given quinine as first line drug. 2.82% (unresponsive to chloroquine and oxytetracycline but with mild disease) were treated with pyrimethamine-sulphamezathine combination for 5 days. One case who did not respond to quinine was treated with quinidine. Recrudescence was seen in 3.67% of patients treated with chloroquine and oxytetracycline. There was no case with renal failure, haemolysis due to G6PD deficiency and black water fever. There was only one death (0.23%) in our series. Self-medication, haphazard therapy and the slogan "Fever may be malaria-take chloroquine" can lead to problems in falciparum malaria.en_US
dc.identifier.citationMehta SR, Naidu G, Chandar V, Singh IP, Johri S, Ahuja RC. Falciparum malaria--present day problems. An experience with 425 cases. Journal of the Association of Physicians of India. 1989 Apr; 37(4): 264-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/86312
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAnimalsen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshChloroquine --therapeutic useen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshInfanten_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshMalaria --drug therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshOxytetracycline --therapeutic useen_US
dc.subject.meshPlasmodium falciparumen_US
dc.titleFalciparum malaria--present day problems. An experience with 425 cases.en_US
dc.typeJournal Articleen_US
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