Efficacy and Safety of Stomatab Capsules® in Improving Oral Health in Recurrent Aphthous Stomatitis: An Open-labeled Clinical Study

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dc.contributor.authorS, Savithaen_US
dc.contributor.authorSoumyaen_US
dc.date.accessioned2023-08-09T06:14:08Z
dc.date.available2023-08-09T06:14:08Z
dc.date.issued2023-05
dc.description.abstractBackground: Recurrent aphthous stomatitis (RAS) is a common ulcerative disease of the oral mucosa, which is difficult to treat. In Ayurveda, several medicinal plants have been evaluated for their anti-inflammatory and antioxidant effects in many oral diseases as an alternative for modern medicines. Method: A study with open-label, non-comparative single-arm design was conducted to evaluate the efficacy of “Stomatab” capsules in improving oral health in 30 subjects with RAS. The secondary objectives were to assess the improvement in oral health and tolerability of the herbal formulation. Subjects were instructed to take one capsule thrice daily after meals for 14 days. Patients were evaluated at three assessment points: screening and baseline (Visit 1, Day 0) with follow-ups done at Visit 2 (Day 5 ± 2) and Visit 3 at the end of the study (Day 14 ± 2). Results: There was a significant reduction in the mean ulcer size from 3.66 ± 1.27 mm (V1) to 0.64 ± 0.78 (V3). The mean number of ulcers reduced from 1.97 ± 0.72 (V1) to 0.90 ± 0.66 (V3). Significant improvement in ulcer-related symptoms of pain (Ruja), burning sensation (Daha) and redness (Raktavarnata) was noted. The total ulcer symptom scores decreased from 7.67 ± 2.38 (V1) to 0.63 ± 0.56 (V3). No side effects were reported by the study participants. Conclusion: These results show that the polyherbal formulation “Stomatab” capsule is safe and effective for the treatment of RAS.en_US
dc.identifier.affiliationsConsultant Ayurvedic Physician Laxmi Polyclinic, Padmanabha Nagar, Bengaluru, Karnatakaen_US
dc.identifier.citationS Savitha, Soumya. Efficacy and Safety of Stomatab Capsules® in Improving Oral Health in Recurrent Aphthous Stomatitis: An Open-labeled Clinical Study. Indian Journal of Clinical Practice. 2023 May; 33(12): 22-29en_US
dc.identifier.issn0971-0876
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/222124
dc.languageenen_US
dc.publisherIJCP Groupen_US
dc.relation.issuenumber12en_US
dc.relation.volume33en_US
dc.source.urihttps://ijcp.in/Pages/Post_Detail.aspx?wid=20578&Efficacy%20and%20Safety%20of%20Stomatab%20Capsules%C2%AE%20in%20Improving%20Oral%20Health%20in%20Recurrent%20Aphthous%20Stomatitis:%20An%20Open-labeled%20Clinical%20Studyen_US
dc.subjectPolyherbalen_US
dc.subjectoral mucosaen_US
dc.subjectulcer sizeen_US
dc.subjectulcer symptom scoreen_US
dc.subjectJasminum grandiflorumen_US
dc.subjectMimusops elengien_US
dc.subjectFicus religiosaen_US
dc.subjectRed ochreen_US
dc.titleEfficacy and Safety of Stomatab Capsules® in Improving Oral Health in Recurrent Aphthous Stomatitis: An Open-labeled Clinical Studyen_US
dc.typeJournal Articleen_US
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